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ONO 3708

Known as: 5-Heptenoic acid, 7-(3-((cyclopentylhydroxyacetyl)amino)-6,6-dimethylbicyclo(3.1.1)hept-2-yl)-, (1S-(1alpha,2beta(Z),3alpha(S*),5alpha))-, ONO-3708 
 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Platelet Aggregation InhibitorsThromboxane A2
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Thromboxane A2 induces itch-associated responses through TP receptors in the skin in mice.
Thromboxane A2 (TXA2), a metabolite of arachidonic acid produced by cyclooxygenase and thromboxane synthase, is thought to… Expand
1998
1998
MECHANISMS OF IMPAIRMENT OF ENDOTHELIUM‐DEPENDENT RELAXATION TO ACETYLCHOLINE IN WATANABE HERITABLE HYPERLIPIDAEMIC RABBIT AORTAS
1. The mechanism of impairment of the endothelium‐dependent relaxation in response to acetylcholine (ACh) in aortas from Watanabe… Expand
1995
1995
Protein tyrosine phosphorylation in human platelets induced by interaction between glycoprotein Ib and von Willebrand factor.
The interaction between von Willebrand factor (vWF) and glycoprotein Ib (GPIb) induced by ristocetin or botrocetin resulted in… Expand
Highly Cited
1994
Highly Cited
1994
Long-term inhibition of NO synthesis promotes atherosclerosis in the hypercholesterolemic rabbit thoracic aorta. PGH2 does not contribute to impaired endothelium-dependent relaxation.
We examined whether prostaglandin (PG) H2, as an endothelium-dependent contracting factor, or the disturbed production of… Expand
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1993
1993
Endothelium‐Dependent Contraction Produced by Acetylcholine and Relaxation Produced by Histamine in Monkey Basilar Arteries
Summary: The present experiments were carried out to investigate the endothelium dependence of the responses to acetylcholine… Expand
Highly Cited
1991
Highly Cited
1991
Prostaglandin H2 as an endothelium-derived contracting factor and its interaction with endothelium-derived nitric oxide.
The possibility that prostaglandin H2 is an endothelium-derived contracting factor (EDCF) was evaluated in rings of thoracic… Expand
Highly Cited
1990
Highly Cited
1990
Prostaglandin H2 may be the endothelium-derived contracting factor released by acetylcholine in the aorta of the rat.
The present experiment was performed to identify endothelium-derived contracting factor produced by acetylcholine stimulation in… Expand
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1989
1989
Effect of OKY-046 and ONO-3708 on liver injury in mice.
The effects of OKY-046, a selective thromboxane A2 (TXA2) synthetase inhibitor, and ONO-3708, a novel TXA2 receptor antagonist… Expand
1989
1989
Effects of ONO-3708, an antagonist of the thromboxane A2/prostaglandin endoperoxide receptor, on platelet aggregation and thrombosis.
The beneficial effects of an antagonist of the thromboxane A2/prostaglandin endoperoxide receptor, 7-[2 alpha,4 alpha… Expand
Highly Cited
1987
Highly Cited
1987
Possible Role of Endothelial Thromboxane A2 in the Resting Tone and Contractile Responses to Acetylcholine and Arachidonic Acid in Canine Cerebral Arteries
Summary The amount of immunoreactive thromboxane B2 (TXB2) released from isolated canine arteries was determined by… Expand
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