Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

ONO 3708

Known as: 5-Heptenoic acid, 7-(3-((cyclopentylhydroxyacetyl)amino)-6,6-dimethylbicyclo(3.1.1)hept-2-yl)-, (1S-(1alpha,2beta(Z),3alpha(S*),5alpha))-, ONO-3708 
 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Platelet Aggregation InhibitorsThromboxane A2
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Thromboxane A2 induces itch-associated responses through TP receptors in the skin in mice.
Thromboxane A2 (TXA2), a metabolite of arachidonic acid produced by cyclooxygenase and thromboxane synthase, is thought to… Expand
Is this relevant?
2000
2000
Thrombin causes endothelium-dependent biphasic regulation of vascular tone in the porcine renal interlobar artery.
Using a method employing front-surface fura-2 fluorometry to measure the cytosolic Ca(2+) concentration, [Ca(2+)](i), the… Expand
Is this relevant?
1995
1995
Protein tyrosine phosphorylation in human platelets induced by interaction between glycoprotein Ib and von Willebrand factor.
The interaction between von Willebrand factor (vWF) and glycoprotein Ib (GPIb) induced by ristocetin or botrocetin resulted in… Expand
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Long-term inhibition of NO synthesis promotes atherosclerosis in the hypercholesterolemic rabbit thoracic aorta. PGH2 does not contribute to impaired endothelium-dependent relaxation.
We examined whether prostaglandin (PG) H2, as an endothelium-dependent contracting factor, or the disturbed production of… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • table 2
Is this relevant?
1993
1993
Role of prostaglandin H2 as an endothelium-derived contracting factor in diabetic state.
This study investigated the possible involvement of prostaglandin H2, an acetylcholine-induced endothelium-derived contracting… Expand
Is this relevant?
1991
1991
Prostaglandin H2 as an endothelium-derived contracting factor and its interaction with endothelium-derived nitric oxide.
The possibility that prostaglandin H2 is an endothelium-derived contracting factor (EDCF) was evaluated in rings of thoracic… Expand
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Prostaglandin H2 may be the endothelium-derived contracting factor released by acetylcholine in the aorta of the rat.
The present experiment was performed to identify endothelium-derived contracting factor produced by acetylcholine stimulation in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1989
1989
Effect of OKY-046 and ONO-3708 on liver injury in mice.
The effects of OKY-046, a selective thromboxane A2 (TXA2) synthetase inhibitor, and ONO-3708, a novel TXA2 receptor antagonist… Expand
Is this relevant?
1987
1987
Possible role of endothelial thromboxane A2 in the resting tone and contractile responses to acetylcholine and arachidonic acid in canine cerebral arteries.
The amount of immunoreactive thromboxane B2 (iTXB2) released from isolated canine arteries was determined by radioimmunoassay… Expand
Is this relevant?
1986
1986
Actions of the novel thromboxane A2 antagonists, ONO-1270 and ONO-3708, on smooth muscle cells of the guinea-pig basilar artery
SummaryThe effects of the novel thromboxane A2 (TXA2) antagonists. ONO-1270 and ONO-3708, on the electrical and mechanical… Expand
  • figure 1
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE