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Norfenfluramine

Known as: Benzeneethanamine, alpha-methyl-3-(trifluoromethyl)-, Norfenfluramine [Chemical/Ingredient] 
A FENFLURAMINE analog that inhibits serotonin uptake and may provoke release of serotonin. It is used as an appetite depressant and an experimental… 
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (2)

Dexnorfenfluraminehydroxyethylnorfenfluramine

Broader (3)

FenfluramineSerotonin AgentsSerotonin Uptake Inhibitors
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Liquid chromatography studies on the pharmacokinetics of phentermine and fenfluramine in brain and blood microdialysates after intraperitoneal administration to rats.
2000
2000
Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action.
1984
1984
Inhibition of gastric emptying by peripheral and central fenfluramine in rats: correlation with anorexia.
Highly Cited
1982
Highly Cited
1982
Differences among 'serotonergic' anorectics in a cross-tolerance paradigm: do they all act on serotonin systems?
1980
1980
Factors controlling the metabolism of phosphatidate by phosphohydrolase and phospholipase A-type activities. Effects of magnesium, calcium and amphiphilic cationic drugs.
Highly Cited
1979
Highly Cited
1979
On the action of nicotine and cotinine on central 5-hydroxytryptamine neurons
Highly Cited
1977
Highly Cited
1977
Factors controlling the activities of phosphatidate phosphohydrolase and phosphatidate cytidylyltransferase. The effects of chlorpromazine, demethylimipramine, cinchocaine, norfenfluramine…
1. Microsomal membranes from rat liver were incubated with ATP, CoA, Mg2+, [14C]palmitate, F- and sn-glycerol 3-phosphate in… 
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
Highly Cited
1973
Highly Cited
1973
Effect of thymoleptics on fenfluramine-induced depletion of brain serotonin in rats.
1973
1973
Differential effects of amphetamine, fenfluramine and norfenfluramine stereoisomers on the increase of striatum homovanillic acid in rats
(+)‐Amphetamine is more effective in increasing the concentration of striatum homovanillic acid (HVA) in rats than the (‐)‐isomer… 
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