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Norfenfluramine

Known as: Benzeneethanamine, alpha-methyl-3-(trifluoromethyl)-, Norfenfluramine [Chemical/Ingredient] 
A FENFLURAMINE analog that inhibits serotonin uptake and may provoke release of serotonin. It is used as an appetite depressant and an experimental… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Recent findings have implicated the 5-hydroxytryptamine 2B (5-HT2B) serotonin receptor in mediating the heart valve fibroplasia… Expand
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Highly Cited
2001
Highly Cited
2001
The present series of studies is the first to investigate the pharmacological mechanisms underlying d-fenfluramine- and d… Expand
Highly Cited
2000
Highly Cited
2000
Background—Serotonergic medications with various mechanisms of action are used to treat psychiatric disorders and are being… Expand
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Highly Cited
2000
Highly Cited
2000
Dexfenfluramine was approved in the United States for long-term use as an appetite suppressant until it was reported to be… Expand
Highly Cited
1999
Highly Cited
1999
The goal of this study was to characterize the agonist pharmacology of human 5‐HT2A, 5‐HT2B and 5‐HT2C (VSV) receptors expressed… Expand
Highly Cited
1993
Highly Cited
1993
Severe depletion of 5-hydroxytryptamine (5-HT) by para-chlorophenylalanine (pCPA, 150 mg/kg per day x3) did not alter the… Expand
Review
1992
Review
1992
Dexfenfluramine stimulates serotoninergic activity by inhibiting serotonin reuptake into presynaptic neurons and by enhancing its… Expand
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Highly Cited
1990
Highly Cited
1990
The optical isomers of fenfluramine and norfenfluramine were administered to rats to examine their relative potency for… Expand
Highly Cited
1990
Highly Cited
1990
Previous research with hypothalamic injection of serotonin (5-HT) has suggested that this monoamine may act within the medial… Expand
Highly Cited
1982
Highly Cited
1982
Summary The anorectic effect of d-norfenfluramine, but not that of d-fenfluramine, was potentiated in reserpine-treated rats… Expand