Norfenfluramine

Known as: Benzeneethanamine, alpha-methyl-3-(trifluoromethyl)-, Norfenfluramine [Chemical/Ingredient] 
A FENFLURAMINE analog that inhibits serotonin uptake and may provoke release of serotonin. It is used as an appetite depressant and an experimental… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1970-2017
051019702017

Papers overview

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2005
2005
S-(+)-Norfenfluramine (SNF)-an active metabolite of the now-banned anorexigen fenfluramine-has been implicated in the drug's… (More)
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Highly Cited
2003
Highly Cited
2003
Recent findings have implicated the 5-hydroxytryptamine 2B (5-HT2B) serotonin receptor in mediating the heart valve fibroplasia… (More)
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Highly Cited
2001
Highly Cited
2001
The present series of studies is the first to investigate the pharmacological mechanisms underlying d-fenfluramine- and d… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Serotonergic medications with various mechanisms of action are used to treat psychiatric disorders and are being… (More)
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Highly Cited
2000
Highly Cited
2000
Dexfenfluramine was approved in the United States for long-term use as an appetite suppressant until it was reported to be… (More)
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Highly Cited
1999
Highly Cited
1999
1. The goal of this study was to characterize the agonist pharmacology of human 5-HT2A, 5-HT2B and 5-HT2C (VSV) receptors… (More)
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1998
1998
N-Ethyl-5-trifluoromethyl-2-aminoindan (ETAI) and 5-trifluoromethyl-2-aminoindan (TAI) were synthesized to examine the effects of… (More)
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1993
1993
Severe depletion of 5-hydroxytryptamine (5-HT) by para-chlorophenylalanine (pCPA, 150 mg/kg per day x3) did not alter the… (More)
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1990
1990
Previous research with hypothalamic injection of serotonin (5-HT) has suggested that this monoamine may act within the medial… (More)
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1983
1983
The abilities of d-fenfluramine (d-F) and that of d-norfenfluramine (d-NF) to inhibit [3H]serotonin ([3H]5-HT) accumulation in… (More)
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