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Norfenfluramine

Known as: Benzeneethanamine, alpha-methyl-3-(trifluoromethyl)-, Norfenfluramine [Chemical/Ingredient] 
A FENFLURAMINE analog that inhibits serotonin uptake and may provoke release of serotonin. It is used as an appetite depressant and an experimental… Expand
National Institutes of Health

Papers overview

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2007
2007
The trifluoromethyl group of fluoxetine 1 and fenfluramine and norfenfluramine, 2 and 3, was substituted by the… Expand
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2005
2005
S-(+)-Norfenfluramine (SNF)—an active metabolite of the now-banned anorexigen fenfluramine—has been implicated in the drug's… Expand
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2004
2004
SummaryThe kinetics of accumulation and elimination of d- and l-fenfluramine (F) and norfenfluramine (NF) have been studied in 8… Expand
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Highly Cited
2003
Highly Cited
2003
Recent findings have implicated the 5-hydroxytryptamine 2B (5-HT2B) serotonin receptor in mediating the heart valve fibroplasia… Expand
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Highly Cited
2001
Highly Cited
2001
The present series of studies is the first to investigate the pharmacological mechanisms underlying d-fenfluramine- and d… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Serotonergic medications with various mechanisms of action are used to treat psychiatric disorders and are being… Expand
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Highly Cited
2000
Highly Cited
2000
Dexfenfluramine was approved in the United States for long-term use as an appetite suppressant until it was reported to be… Expand
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Highly Cited
1999
Highly Cited
1999
1. The goal of this study was to characterize the agonist pharmacology of human 5-HT2A, 5-HT2B and 5-HT2C (VSV) receptors… Expand
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1993
1993
Severe depletion of 5-hydroxytryptamine (5-HT) by para-chlorophenylalanine (pCPA, 150 mg/kg per day x3) did not alter the… Expand
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1990
1990
Previous research with hypothalamic injection of serotonin (5-HT) has suggested that this monoamine may act within the medial… Expand
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