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Fenfluramine

Known as: Fenfluramine [Chemical/Ingredient], Benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-, Fenfluramina 
An amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant property. Fenfluramine, which was part of the Fen-Phen anti… 
National Institutes of Health

Related topics

Related topics

34 relations

Broader (6)

Appetite DepressantsEthylaminesPhenethylaminesSerotonin Agents
Autistic DisorderBulimiaDexfenfluramineDrug Allergy

Narrower (10)

Fenfluramine HydrochlorideITA 213IsomerideNorfenfluramine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Valvular heart disease associated with benfluorex therapy : results from the French multicentre registry
Department of Cardiology, University Hospital Brest, Brest, France; Department of Cardiology, University Hospital Amiens, Amiens… 
1995
1995
Determination of fenfluramine enantiomers in pharmaceutical formulations by capillary zone electrophoresis
SummaryCapillary zone electrophoresis has been used for the enantiomeric separation of racemic ortho-fenfluramine and meta… 
Highly Cited
1990
Highly Cited
1990
Fenfluramine augmentation of serotonin reuptake blockade antiobsessional treatment.
Seven patients who met DSM-III-R criteria for obsessive compulsive disorder and had only a partial response to the serotonin… 
1989
1989
Cortisol, ACTH, prolactin and beta-endorphin responses to fenfluramine administration in major-depressed patients.
In the past, some researchers found increased cortisol and prolactin responses to the administration of fenfluramine in major… 
Review
1988
Review
1988
The Fenfluramine Challenge Test in the Affective Spectrum: A Possible Marker of Endogeneity and Severity
In order to investigate the role of serotonergic mechanisms in depressive disorders, the fenfluramine challenge test was… 
1985
1985
Fenfluramine delays gastric emptying of solid food.
The effect of a single dose of (+/-)-fenfluramine hydrochloride (40 mg) on gastric emptying of a mixed solid and liquid meal was… 
1983
1983
Decreased accumulation of brain 5‐hydroxytryptophan after decarboxylase inhibition in rats treated with fenfluramine, norfenfluramine or p‐chloroamphetamine
Fenfluramine, norfenfluramine and p-chloroamphetamine all lead to rapid but long-lasting depletion of brain 5-hydroxytryptamine… 
1977
1977
Emotional symptomatology in obese patients treated with fenfluramine and dextroamphetamine
Synopsis Emotional symptomatology data on 78 obese females treated for 3 weeks with fenfluramine, dextroamphetamine, or placebo… 
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
1975
1975
Fenfluramine in man: hypophagia associated with diminished serotonin turnover.
A double-blind trial of orally administered fenfluramine was conducted in 7 non-obese adults with various neurological disorders…