FAQ

Fenfluramine Hydrochloride

Known as: Fenfluramine Hydrochloride [Chemical/Ingredient], Hydrochloride, Fenfluramine 
The hydrochloride salt of fenfluramine, an amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant properties. Fenfluramine… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2013
05101519652013

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10 relations
Autistic DisorderBulimiaDrug AllergyGlaucoma
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Broader (1)

Fenfluramine

Narrower (1)

Pondimin

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Fenfluramine Hydrochloride
Obesity
Drug Allergy
Schizophrenia
Autistic Disorder
Glaucoma

Papers overview

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2010
2010
A serotonin and melanocortin circuit mediates D-fenfluramine anorexia.
D-Fenfluramine (D-Fen) increases serotonin (5-HT) content in the synaptic cleft and exerts anorexigenic effects in animals and… (More)
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Highly Cited
2003
Highly Cited
2003
Positron emission tomography of regional brain metabolic responses to a serotonergic challenge and lethality of suicide attempts in major depression.
BACKGROUND Lower serotonergic activity correlates with high-lethality suicide attempts in major depression. Postmortem studies of… (More)
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Highly Cited
2000
Highly Cited
2000
A fenfluramine-activated FDG-PET study of borderline personality disorder.
BACKGROUND Impulsive aggression in patients with personality disorders is associated with diminished levels of cerebrospinal… (More)
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Highly Cited
2000
Highly Cited
2000
A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivity.
This study presents preliminary evidence of an association between polymorphic variation in the gene for monoamine oxidase-A… (More)
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2000
2000
Serotonin, impulsivity, and alcohol use disorders in the older adolescent: a psychobiological study.
BACKGROUND Alcohol use disorders (AUDs) among adolescents are associated with a high prevalence of conduct disorder (CD), much as… (More)
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Highly Cited
1999
Highly Cited
1999
d,l-fenfluramine Response in Impulsive Personality Disorder Assessed with [18F]fluorodeoxyglucose Positron Emission Tomography
Reduced serotonergic activity has been associated with impulsive aggression in personality disordered patients in metabolite and… (More)
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Highly Cited
1999
Highly Cited
1999
Aggression and anger-related traits associated with a polymorphism of the tryptophan hydroxylase gene.
BACKGROUND Central nervous system (CNS) serotonergic activity correlates inversely with human aggressive behavior, and individual… (More)
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1992
1992
Serotonergic function in obsessive-compulsive disorder. Behavioral and neuroendocrine responses to oral m-chlorophenylpiperazine and fenfluramine in patients and healthy volunteers.
To evaluate serotonergic (5-hydroxytryptamine) function in obsessive-compulsive disorder, behavioral and neuroendocrine responses… (More)
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Highly Cited
1989
Highly Cited
1989
Serotonergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behavior.
Dysfunction of the central serotonergic system has been variously associated with depression and with suicidal and/or impulsive… (More)
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1984
1984
A double-blind clinical trial in weight control. Use of fenfluramine and phentermine alone and in combination.
We performed a double-blind, controlled clinical trial comparing phentermine resin (30 mg in the morning), fenfluramine… (More)
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