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Dexfenfluramine

Known as: Dexfenfluramine [Chemical/Ingredient], Dexfenfluraminum, (S)-N-Ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine 
The S-isomer of FENFLURAMINE. It is a serotonin agonist and is used as an anorectic. Unlike fenfluramine, it does not possess any catecholamine… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
After weighing the risks and benefits, the FDA recently approved two new drugs as adjuncts to a reduced-calorie diet and… Expand
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Highly Cited
2004
Highly Cited
2004
Dexfenfluramine associated pulmonary arterial hypertension occurring in a patient with hereditary haemorrhagic telangiectasia… Expand
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Highly Cited
2000
Highly Cited
2000
Background—Serotonergic medications with various mechanisms of action are used to treat psychiatric disorders and are being… Expand
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Review
1999
Review
1999
I. Introduction II. Criteria for Evaluating the Efficacy of Antiobesity Treatment III. Physiological and Pharmacological… Expand
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Highly Cited
1999
Highly Cited
1999
Brain-derived neurotrophic factor (BDNF) has trophic effects on serotonergic (5-HT) neurons in the central nervous system… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The appetite-suppressant drug fenfluramine, usually given in combination with phentermine, has been reported to be… Expand
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Highly Cited
1997
Highly Cited
1997
1 The mechanism underlying 5‐hydroxytryptamine (5‐HT) and/or dopamine release induced by (+)‐amphetamine ((+)‐Amph), 3,4… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND The appetite suppressant aminorex fumarate is thought to have caused an epidemic of pulmonary hypertension in Europe… Expand
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Highly Cited
1992
Highly Cited
1992
The abilities of the substituted amphetamines 3,4-methylenedioxymethamphetamine (MDMA), methamphetamine, p-chloroamphetamine (PCA… Expand
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Highly Cited
1989
Highly Cited
1989
In a randomised, placebo-controlled, double-blind study, 822 obese patients of both sexes were given either dexfenfluramine (dF… Expand
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