FAQ

Serotonin Uptake Inhibitors

Known as: Uptake Inhibitors, 5 Hydroxytryptamine, Reuptake Inhibitors, Serotonin, Inhibitors, 5-HT Uptake 
Compounds that specifically inhibit the reuptake of serotonin in the brain.

Topic mentions per year

Topic mentions per year

1947-2018
050019472017

Related topics

Related topics

44 relations
Adrenergic Uptake InhibitorsAntidepressive Agents, Second-GenerationIn BloodReceptors, Serotonin, 5-HT2
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Narrower (27)

AmoxapineCitalopramClomipramineFenclonine
(More)

Broader (1)

neurotransmitter antagonist

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
Serotonin Uptake Inhibitors
agonists
Fluoxetine
olanzapine
Citalopram
Paroxetine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study
OBJECTIVE To characterise whether some selective serotonin reuptake inhibitor (SSRI) antidepressants reduce tamoxifen's… (More)
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Highly Cited
2008
Highly Cited
2008
Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses.
BACKGROUND In animal models, variations in early maternal care are associated with differences in hypothalamic-pituitary-adrenal… (More)
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Highly Cited
2008
Highly Cited
2008
Sex-specific programming of offspring emotionality after stress early in pregnancy.
Prenatal stress is associated with an increased vulnerability to neurodevelopmental disorders, including autism and schizophrenia… (More)
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Highly Cited
2007
Highly Cited
2007
First-Trimester Use of Selective Serotonin-Reuptake Inhibitors and the Risk of Birth Defects.
BACKGROUND The risk of birth defects after antenatal exposure to selective serotonin-reuptake inhibitors (SSRIs) remains… (More)
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Highly Cited
2006
Highly Cited
2006
Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice.
OBJECTIVE Selective serotonin reuptake inhibitors (SSRIs) are widely used to treat depression, but the rates, timing, and… (More)
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Highly Cited
2005
Highly Cited
2005
CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment.
BACKGROUND The efficacy of tamoxifen therapy for the treatment of breast cancer varies widely among individuals. Plasma… (More)
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Highly Cited
2004
Highly Cited
2004
Serotonin transporter occupancy of five selective serotonin reuptake inhibitors at different doses: an [11C]DASB positron emission tomography study.
OBJECTIVE Minimum therapeutic doses of paroxetine and citalopram produce 80% occupancy for the serotonin (5-HT) transporter (5… (More)
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Highly Cited
2003
Highly Cited
2003
Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial.
CONTEXT Depression and low perceived social support (LPSS) after myocardial infarction (MI) are associated with higher morbidity… (More)
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Highly Cited
2000
Highly Cited
2000
Selective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-analysis of efficacy and tolerability.
BACKGROUND A meta-analysis of the efficacy and tolerability of selective serotonin reuptake inhibitors (SSRIs) against tricyclic… (More)
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Highly Cited
1998
Highly Cited
1998
Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
Depression with psychotic features has been shown to respond to selective serotonin reuptake inhibitors (SSRIs). The serotonin… (More)
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