Fenclonine

Known as: para-Chlorophenylalanine, PCPA, DL-PCPA 
A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
U1 snRNP (U1), in addition to its splicing role, protects pre-mRNAs from drastic premature termination by cleavage and… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND & AIMS Mucosal changes in inflammatory bowel disease are characterized by ulcerative lesions accompanied by a… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The mechanism of pulmonary artery smooth muscle cell (PA-SMC) hyperplasia in idiopathic pulmonary artery hypertension… (More)
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Highly Cited
2004
Highly Cited
2004
Although tasks assessing the role of dopamine in effort-reward decisions are similar to those concerned with the role of… (More)
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Highly Cited
2001
Highly Cited
2001
Anatomical evidence indicates that medial prefrontal cortex (mPFC) neurons project to the dorsal raphe nucleus (DR). In this… (More)
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Highly Cited
1999
Highly Cited
1999
Rationale: The forced swimming test (FST) is a behavioral test in rodents that predicts the clinical efficacy of many types of… (More)
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Highly Cited
1999
Highly Cited
1999
STUDY OBJECTIVES To perform a population-based study addressing the demography, epidemiology, management, and outcome of out-of… (More)
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Highly Cited
1996
Highly Cited
1996
In a transgenic mouse line (Tg8) deficient for the gene encoding monoamine oxidase A (MAOA), we show that the primary… (More)
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Highly Cited
1995
Highly Cited
1995
In this study, the involvement of serotonergic and dopaminergic receptors in the modulation of the head-twitch (HTW) response to… (More)
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Highly Cited
1990
Highly Cited
1990
Amphetamine and cocaine are stimulant drugs that act on central monoaminergic neurons to produce both acute psychomotor… (More)
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