Share This Author
Sedation and Anesthesia Mediated by Distinct GABAA Receptor Isoforms
Findings show that anesthesia and sedation are mediated by distinct GABAA receptor subtypes, and that the β2 subunit mediates the sedative properties of anesthetics.
Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus
Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression
The neurobiological basis of binge-eating disorder
Behavioral and biochemical characterization of a mutant mouse strain lacking d-amino acid oxidase activity and its implications for schizophrenia
Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice.
Decreased social behaviour following 3,4-methylenedioxymethamphetamine (MDMA) is accompanied by changes in 5-HT2A receptor responsivity
Modulation of [3H]MK-801 binding to NMDA receptors in vivo and in vitro.
The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943…
The Behavioral and Neurochemical Effects of a Novel d-Amino Acid Oxidase Inhibitor Compound 8 [4H-Thieno [3,2-b]pyrrole-5-carboxylic Acid] and d-Serine
- Sean M. Smith, J. Uslaner, P. Hutson
- BiologyJournal of Pharmacology and Experimental…
- 16 December 2008
It is demonstrated that pharmacological inhibition of DAAO significantly increases d-serine concentration in the periphery and central nervous system and that high doses of d-Serine attenuated both amphetamine-induced psychomotor activity and dopamine release and also improved performance in novel object recognition.