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Nelfinavir

Known as: NFV, Nelfinavir [Chemical/Ingredient] 
A synthetic antiviral agent that selectively binds to and inhibits human immunodeficiency virus (HIV) protease. Nelfinavir has activity against HIV 1… 
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (4)

AG 1343M8-nelfinavirNelfinavir MesylateViracept
Acquired Immunodeficiency SyndromeAstemizoleCYP2C19 protein, humanCYP3A7 protein, human

Broader (4)

Antiviral AgentsHIV Protease InhibitorsIsoquinolinesProtease Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Normalized Feature Vectors: A Novel Alignment-Free Sequence Comparison Method Based on the Numbers of Adjacent Amino Acids
Based on all kinds of adjacent amino acids (AAA), we map each protein primary sequence into a 400 by (L-1) matrix M. In addition… 
Highly Cited
2013
Highly Cited
2013
Antiviral Resistance and Correlates of Virologic Failure in the first Cohort of HIV-Infected Children Gaining Access to Structured Antiretroviral Therapy in Lima, Peru: A Cross-Sectional Analysis
BackgroundThe impact of extended use of ART in developing countries has been enormous. A thorough understanding of all factors… 
Highly Cited
2011
Highly Cited
2011
Triple-Antiretroviral Prophylaxis to Prevent Mother-To-Child HIV Transmission through Breastfeeding—The Kisumu Breastfeeding Study, Kenya: A Clinical Trial
Timothy Thomas and colleagues report the results of the Kisumu breastfeeding study (Kenya), a single-arm trial that assessed the… 
Highly Cited
2007
Highly Cited
2007
Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo
Purpose: The development of new cancer drugs is slow and costly. HIV protease inhibitors are Food and Drug Administration… 
Highly Cited
2007
Highly Cited
2007
Comparison of the inhibitory activity of anti-HIV drugs on P-glycoprotein.
Highly Cited
2005
Highly Cited
2005
Blockade of HERG channels by HIV protease inhibitors
Highly Cited
2000
Highly Cited
2000
Determination of twelve antiretroviral agents in human plasma sample using reversed-phase high-performance liquid chromatography.
Highly Cited
2000
Highly Cited
2000
HIV protease inhibitors block adipogenesis and increase lipolysis in vitro.
Review
1996
Review
1996
Antiretroviral therapy in adults.
In 1993, HIV became the leading cause of death among persons 25 to 44 years old (Centers for Disease Control and Prevention [CDC… 
Highly Cited
1989
Highly Cited
1989
Pollinator abundance, morphology, and flower visitation rate: analysis of the “quantity” component in a plant-pollinator system
SummaryAbundance and flower visitation rate of the pollinators of Lavandula latifolia (Labiatae), an insect-pollinated shrub… 
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