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Astemizole

Known as: Astemizolum, Astemizole [Chemical/Ingredient], 1-(P-Fluorobenzyl)-2-((1-(2-(P-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole 
A synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1… 
National Institutes of Health

Related topics

Related topics

50 relations
200 ML Fluconazole 2 MG/ML Injection24 HR Clarithromycin 500 MG Extended Release Oral TabletAllergic ConjunctivitisAstemizole:MCnc:Pt:Ser/Plas:Qn

Narrower (12)

AlermizolAsteminaEsmacenHismanal

Broader (1)

Anti-Allergic Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
QT prolongation in anaesthetized guinea‐pigs: an experimental approach for preliminary screening of torsadogenicity of drugs and drug candidates
Many non‐cardiovascular drugs can prolong the QT interval of the electrocardiogram (ECG); this is an accessory property not… 
2003
2003
Solid-phase synthesis of benzimidazole libraries biased for RNA targets
2000
2000
A new model of allergic rhinitis in rats by topical sensitization and evaluation of H(1)-receptor antagonists.
Review
2000
Review
2000
Amprenavir: a new human immunodeficiency virus type 1 protease inhibitor.
1999
1999
In vitro inhibition of human liver drug metabolizing enzymes by second generation antihistamines.
1996
1996
Rush immunotherapy: experience with a one-day schedule.
Review
1994
Review
1994
Possible interactions with terfenadine or astemizole.
Concurrent use of terfenadine or astemizole with erythromycin or ketoconazole can prolong the QT interval and produce potentially… 
1991
1991
Neuropathic pain behavior in rats depends on the afferent input from nerve-end neuroma including histamine-sensitive C-fibers
1991
1991
Effect of the histamine-1 antagonist astemizole alone or with omeprazole on rat gastric mucosa.
The stimulation of acid secretion by gastrin may in the rat be explained solely by gastrin-induced histamine release. This study… 
1991
1991
Oral allergy syndrome: the effect of astemizole
The effect of treatment with astemizole (Hismanal®) on symptoms elicited by ingestion of hazelnuts in birch pollen‐allergic… 
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