Isoquinolines

Known as: 2 benzazine, Isoquinolines [Chemical/Ingredient], isoquinoline 
A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1946-2017
05010019462016

Papers overview

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2010
2010
Berberine, an isoquinoline alkaloid is reported to modulate several neurotransmitter systems like N-methyl-D-aspartate, nitric… (More)
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Highly Cited
2009
Highly Cited
2009
UNLABELLED Schizophrenia is a chronic and disabling brain disease characterized by psychotic episodes with unknown etiology. It… (More)
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Highly Cited
2002
Highly Cited
2002
Roots and barks of various Berberis species are used as folk remedy for the treatment of various inflammatory diseases such as… (More)
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2002
2002
Endogenous isoquinoline (IQ) derivatives structurally related to the selective dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6… (More)
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Highly Cited
1998
Highly Cited
1998
1-[N, O-Bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine (KN-62) and N-[1-[N-methyl-p-(5 isoquinolinesulfonyl… (More)
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Highly Cited
1997
Highly Cited
1997
1. Extracellular adenosine 5'-triphosphate (ATP) is an agonist for a P2Z receptor on human lymphocytes which mediates opening of… (More)
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1995
1995
Mitochondrial respiratory failure secondary to complex I inhibition may contribute to the neurodegenerative process underlying… (More)
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1992
Highly Cited
1992
The mitochondrial benzodiazepine receptor (mBzR) has been solubilized with retention of reversible ligand binding, and the… (More)
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1990
1990
A series of 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines were tested as substrates and/or inactivators of… (More)
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Highly Cited
1984
Highly Cited
1984
Naphthalenesulfonamides such as N-(6-amino-hexyl)-5-chloro-1-naphthalenesulfonamide (W-7) are potent calmodulin (CaM) antagonists… (More)
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