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A-317567

National Institutes of Health

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2 relations

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IsoquinolinesNaphthalenes

Papers overview

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2013
2013
NEITHER SYSTEMIC NOR INTRAVESICAL ADMINISTRATION OF A-317567, AN ACID-SENSING ION CHANNEL BLOCKER AFFECT THE LOWER URINARY TRACT ACTIVITY IN DECEREBRATE UNANESTHETIZED MICE
Hypothesis / aims of study Acid-sensing ion channels (ASICs) represent an H + -gated subgroup of the degenerin/epithelial Na… 
2012
2012
The acidic pH-induced structural changes in Pin1 as revealed by spectral methodologies.
2011
2011
Chronic hypoxia-induced acid-sensitive ion channel expression in chemoafferent neurons contributes to chemoreceptor hypersensitivity.
Previously we demonstrated that chronic hypoxia (CH) induces an inflammatory condition characterized by immune cell invasion and… 
2010
2010
INTRAVESICAL INFUSION OF A NON-AMILORIDE BLOCKER OF ACID-SENSING ION CHANNELS FAILS TO AFFECT LOWER URINARY TRACT ACTIVITY IN UNANESTHETIZED DECEREBRATE MICE
Hypothesis / aims of study Painful inflammation and ischemic conditions are accompanied by a decrease in the extracellular pH… 
2008
2008
Role played by acid-sensitive ion channels in evoking the exercise pressor reflex.
The exercise pressor reflex arises from contracting skeletal muscle and is believed to play a role in evoking the cardiovascular… 
2007
2007
Evidence that A‐317567 is a selective ASIC antagonist for thin fiber muscle afferents in decerebrate cats
Lactic acid is widely hypothesized to accumulate in contracting muscle to activate the thin fiber muscle afferents causing the… 
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