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Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets.
- Chen-Yu Zhang, L. Parton, B. Lowell
- Biology, MedicineCell metabolism
- 1 June 2006
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer
- A. Wolfe, Kamini Singh, H. Wendel
- BiologyNature
- 27 July 2014
TLDR
Antitumor Activity and Mechanism of Action of the Cyclopenta[b]benzofuran, Silvestrol
- R. Cencic, M. Carrier, J. Pelletier
- BiologyPloS one
- 29 April 2009
TLDR
Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State
- S. Santagata, M. Mendillo, S. Lindquist
- BiologyScience
- 19 July 2013
TLDR
nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs.
- V. Gandin, Laia Masvidal, I. Topisirovic
- BiologyGenome research
- 16 March 2016
TLDR
Targeting heat shock response to sensitize cancer cells to proteasome and Hsp90 inhibitors.
- Nava Zaarur, V. Gabai, J. Porco, S. Calderwood, M. Sherman
- Biology, ChemistryCancer research
- 1 February 2006
TLDR
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.
- Marie-Ève Bordeleau, F. Robert, J. Pelletier
- Biology, ChemistryThe Journal of clinical investigation
- 1 July 2008
TLDR
Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity.
- M. Liang, Sujata Bardhan, T. Gilmore
- Biology, ChemistryBiochemical pharmacology
- 28 February 2006
How Proteins Bind Macrocycles
- Elizabeth A. Villar, D. Beglov, A. Whitty
- Chemistry, BiologyNature chemical biology
- 17 June 2014
TLDR
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