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Nelfinavir Mesylate
Known as:
Nelfinavir Monomethane Sulfonate
, Sulfonate, Nelfinavir Monomethane
, Mesylate, Nelfinavir
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The mesylate salt form of nelfinavir, a synthetic antiviral agent that selectively binds to and inhibits human immunodeficiency virus (HIV) protease…
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National Institutes of Health
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Related topics
Related topics
17 relations
Narrower (2)
AG 1343
Viracept
Acquired Immunodeficiency Syndrome
Astemizole
Cisapride
Drug Allergy
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Broader (4)
Antiviral Agents
Isoquinolines
Nelfinavir
Sulfonic Acids
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Precipitation in the small intestine may play a more important role in the in vivo performance of poorly soluble weak bases in the fasted state: case example nelfinavir.
Yasushi Shono
,
E. Jantratid
,
J. Dressman
European journal of pharmaceutics and…
2011
Corpus ID: 8425163
Highly Cited
2001
Highly Cited
2001
Circulating Metabolites of the Human Immunodeficiency Virus Protease Inhibitor Nelfinavir in Humans: Structural Identification, Levels in Plasma, and Antiviral Activities
Kanyin E. Zhang
,
E. Wu
,
+7 authors
S. Webber
Antimicrobial Agents and Chemotherapy
2001
Corpus ID: 44534215
ABSTRACT Nelfinavir mesylate (Viracept, formally AG1343) is a potent and orally bioavailable human immunodeficiency virus (HIV…
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Review
1999
Review
1999
Nelfinavir Mesylate: A Protease Inhibitor
V. Pai
,
M. Nahata
The Annals of Pharmacotherapy
1999
Corpus ID: 24066955
OBJECTIVE: To review the clinical pharmacology, pharmacokinetics, efficacy, adverse effects, drug interactions, and dosage…
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Highly Cited
1999
Highly Cited
1999
Treatment of human immunodeficiency virus 1-infected infants and children with the protease inhibitor nelfinavir mesylate.
P. Krogstad
,
A. Wiznia
,
+10 authors
Y. Bryson
Clinical Infectious Diseases
1999
Corpus ID: 22278116
An open-label study was conducted of nelfinavir mesylate, given with reverse transcriptase inhibitors to human immunodeficiency…
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Highly Cited
1998
Highly Cited
1998
A preliminary evaluation of nelfinavir mesylate, an inhibitor of human immunodeficiency virus (HIV)-1 protease, to treat HIV infection.
M. Markowitz
,
M. Conant
,
+10 authors
D. Ho
Journal of Infectious Diseases
1998
Corpus ID: 33389786
A phase I/II dose-ranging open-label 28-day monotherapy study of the safety, pharmacokinetics, and antiviral activity of…
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Highly Cited
1998
Highly Cited
1998
Genotypic and Phenotypic Characterization of Human Immunodeficiency Virus Type 1 Variants Isolated from Patients Treated with the Protease Inhibitor Nelfinavir
A. Patick
,
M. Durán
,
+7 authors
M. Markowitz
Antimicrobial Agents and Chemotherapy
1998
Corpus ID: 7811032
ABSTRACT Nelfinavir mesylate (formerly AG1343) is a potent and selective inhibitor of human immunodeficiency virus (HIV) protease…
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Highly Cited
1998
Highly Cited
1998
Characterization of the selectivity and mechanism of human cytochrome P450 inhibition by the human immunodeficiency virus-protease inhibitor nelfinavir mesylate.
J. Lillibridge
,
B. Liang
,
+4 authors
C. Lee
Drug Metabolism And Disposition
1998
Corpus ID: 13209992
In vitro studies with human liver microsomes and P450 probe substrates were performed to characterize selectivity and mechanism…
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Review
1997
Review
1997
HIV-1 protease inhibitors. A review for clinicians.
S. Deeks
,
M. Smith
,
M. Holodniy
,
J. Kahn
JAMA
1997
Corpus ID: 11461936
OBJECTIVE The clinical care of people infected with human immunodeficiency virus (HIV) has been substantially affected by the…
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Highly Cited
1996
Highly Cited
1996
Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of dolasetron. Comparison with other indole-containing 5-HT3 antagonists.
P. Sanwald
,
M. David
,
J. Dow
Drug Metabolism And Disposition
1996
Corpus ID: 20204268
Dolasetron mesilate [(2 alpha, 6 alpha, 8 alpha, 9a beta)-octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl-1H-indole-3-c arboxylate…
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Highly Cited
1988
Highly Cited
1988
21-Aminosteroid lipid peroxidation inhibitor U74006F protects against cerebral ischemia in gerbils.
E. Hall
,
K. E. Pazara
,
J. Braughler
Stroke
1988
Corpus ID: 2365295
U74006F (21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-16 alpha-methylpregna-1,4,9(11)-triene-3,20-dione…
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