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Protease Inhibitors

Known as: Peptide Hydrolase Inhibitors, Inhibitors, Peptidase, Inhibitors, Peptide Peptidohydrolase 
A compound that interferes with the ability of certain enzymes to break down proteins. Some protease inhibitors can keep a virus from making copies… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Hepatitis C virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected… Expand
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Highly Cited
2001
Highly Cited
2001
Nonadherence to medication is a major obstacle to successful medical treatment. Despite the efforts of providers, pharmaceutical… Expand
Review
2000
Review
2000
Improved therapeutic strategies, including the introduction of protease inhibitors, have led to a striking decrease in HIV… Expand
Highly Cited
2000
Highly Cited
2000
ObjectiveTo examine the relationship between adherence, viral suppression and antiretroviral resistance in HIV-infected homeless… Expand
Highly Cited
2000
Highly Cited
2000
Chronic pancreatitis (CP) is a continuing or relapsing inflammatory disease of the pancreas. In approximately one-third of all… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The prevalence and severity of lipodystrophy syndrome with long-term therapy for HIV-1 infection that includes a… Expand
Highly Cited
1998
Highly Cited
1998
Objective:To describe a syndrome of peripheral lipodystrophy (fat wasting of the face, limbs and upper trunk), hyperlipidaemia… Expand
Highly Cited
1998
Highly Cited
1998
BACKGROUND AND METHODS National surveillance data show recent, marked reductions in morbidity and mortality associated with the… Expand
Highly Cited
1998
Highly Cited
1998
Currently available HIV-1 protease inhibitors are potent agents in the therapy of HIV-1 infection. However, limited oral… Expand
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Highly Cited
1995
Highly Cited
1995
INHIBITORS of the human immunodeficiency virus type 1 (HIV-1) protease have entered clinical study as potential therapeutic… Expand