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Protease Inhibitors

Known as: Peptide Hydrolase Inhibitors, Inhibitors, Peptidase, Inhibitors, Peptide Peptidohydrolase 
A compound that interferes with the ability of certain enzymes to break down proteins. Some protease inhibitors can keep a virus from making copies… 
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Hepatitis C virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected… 
Highly Cited
2001
Highly Cited
2001
Nonadherence to medication is a major obstacle to successful medical treatment. Despite the efforts of providers, pharmaceutical… 
Review
2000
Review
2000
Improved therapeutic strategies, including the introduction of protease inhibitors, have led to a striking decrease in HIV… 
Highly Cited
2000
Highly Cited
2000
ObjectiveTo examine the relationship between adherence, viral suppression and antiretroviral resistance in HIV-infected homeless… 
Highly Cited
2000
Highly Cited
2000
Chronic pancreatitis (CP) is a continuing or relapsing inflammatory disease of the pancreas. In approximately one-third of all… 
Highly Cited
2000
Highly Cited
2000
We describe here eleven different mutations in SPINK5, encoding the serine protease inhibitor LEKTI, in 13 families with… 
Highly Cited
1999
Highly Cited
1999
Programmed cell death (PCD) is a process by which cells in many organisms die. The basic morphological and biochemical features… 
Highly Cited
1998
Highly Cited
1998
Objective:To describe a syndrome of peripheral lipodystrophy (fat wasting of the face, limbs and upper trunk), hyperlipidaemia… 
Highly Cited
1998
Highly Cited
1998
BACKGROUND AND METHODS National surveillance data show recent, marked reductions in morbidity and mortality associated with the… 
Highly Cited
1998
Highly Cited
1998
Currently available HIV-1 protease inhibitors are potent agents in the therapy of HIV-1 infection. However, limited oral…