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PI3 gene

Known as: SKALP, WAP3, trappin-2 
This gene plays a role in the inhibition of elastase activity.
National Institutes of Health

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Related topics

6 relations
ElafinPI3 protein, humanProtease InhibitorsProtein Degradation Inhibition

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PI3 wt Allele

Papers overview

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2011
2011
IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides
The airway epithelium forms a barrier against infection but also produces antimicrobial peptides (AMPs) and other inflammatory… 
2011
2011
A simple high pH liquid chromatography-tandem mass spectrometry method for basic compounds: application to ephedrines in doping control analysis.
2007
2007
Human Pre-Elafin Inhibits a Pseudomonas aeruginosa-Secreted Peptidase and Prevents Its Proliferation in Complex Media
ABSTRACT Pseudomonas aeruginosa is a life-threatening opportunist human pathogen frequently associated with lung inflammatory… 
2007
2007
Characterization of human pre-elafin mutants: full antipeptidase activity is essential to preserve lung tissue integrity in experimental emphysema.
Pre-elafin is a tight-binding inhibitor of neutrophil elastase and myeloblastin; two enzymes thought to contribute to tissue… 
2001
2001
Genotyping of simple and compound short tandem repeat loci using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.
The utility of electrospray ionization Fourier transform ion cyclotron resonance (ESI-FIICR) mass spectrometry as a new approach… 
2000
2000
Gene Transfer of the Serine Elastase Inhibitor Elafin Protects Against Vein Graft Degeneration
Background—Leukocyte infiltration and serine elastase activity lead to smooth muscle cell proliferation in association with… 
1999
1999
Differential gene expression in neoplastic and human papillomavirus-immortalized oral keratinocytes
We have previously demonstrated that normal human oral keratinocytes immortalized by transfection with human papillomavirus type… 
1996
1996
Accelerated Evolution in Inhibitor Domains of Porcine Elafin Family Members (*)
Through the analysis of the porcine gene encoding the elastase inhibitor elafin, we demonstrated that there are at least three… 
1994
1994
Assignment of the human gene encoding the epidermal serine proteinase inhibitor SKALP (PI3) to chromosome region 20q12-->q13.
Recently we isolated a cDNA clone corresponding to an epidermal serine proteinase inhibitor named SKALP (skin-derived… 
Highly Cited
1992
Highly Cited
1992
Primary structure of the human elafin precursor preproelafin deduced from the nucleotide sequence of its gene and the presence of unique repetitive sequences in the prosegment.
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