Elafin

Known as: Protease Inhibitor 3, Skin derived, Skin Derived Antileukoproteinase, Peptidase Inhibitor 3, Skin derived 
A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Elafin, a natural protease inhibitor expressed in healthy intestinal mucosa, has pleiotropic anti-inflammatory properties in… (More)
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Review
2011
Review
2011
Elafin is an endogenous human protein composed of an N-terminal transglutaminase substrate motif and a C-terminal WAP (whey… (More)
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Highly Cited
2008
Highly Cited
2008
Graft-versus-host disease (GVHD), the major complication of allogeneic bone marrow transplantation, affects the skin, liver, and… (More)
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2003
2003
Elafin is a skin-derived serine-protease inhibitor. It is thought to be important to prevent human leukocyte elastase-mediated… (More)
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2003
2003
The control of lung inflammation is of paramount importance in a variety of acute pathologies, such as pneumonia, the acute… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Increased serine elastase activity has been implicated in the vascular remodeling associated with chronic hypoxia… (More)
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2001
2001
Lipopolysaccharide (LPS) is a mediator of inflammatory lung injury. Selective augmentation of host defense molecules such as… (More)
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Highly Cited
1994
Highly Cited
1994
The regulation of the activity of potentially harmful proteinases secreted by neutrophils during inflammation is important for… (More)
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Highly Cited
1991
Highly Cited
1991
Elafin, a human skin derived inhibitor of human leukocyte elastase, was tested for inhibitory activity against proteinase 3, an… (More)
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Highly Cited
1990
Highly Cited
1990
A potent inhibitor of human leukocyte elastase (EC 3.4.21.37) and porcine pancreatic elastase (EC 3.4.21.36) was purified to… (More)
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