PI3 protein, human

Known as: protease inhibitor 3, skin-derived (SKALP), human, WFDC14 protein, human, elafin protein, human 
Elafin (117 aa, ~12 kDa) is encoded by the human PI3 gene. This protein plays a role in the inhibition of neutrophil and pancreatic elastase… (More)

Topic mentions per year

Topic mentions per year

1969-2018
020040060019692018

Papers overview

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Review
2015
Review
2015
Apoptosis of retinal ganglion cells (RGCs) in glaucoma causes progressive visual field loss, making it the primary cause of… (More)
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Highly Cited
2011
Highly Cited
2011
Prostate cancer is characterized by its dependence on androgen receptor (AR) and frequent activation of PI3K signaling. We find… (More)
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Highly Cited
2008
Highly Cited
2008
Phosphatidylinositol-3-kinase (PI3K) pathway deregulation is a common event in human cancer, either through inactivation of the… (More)
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Highly Cited
2007
Highly Cited
2007
A large-scale RNA interference screen to discover genes involved in trastuzumab resistance in breast cancer identified only PTEN… (More)
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Highly Cited
2006
Highly Cited
2006
The PI3 kinase family of lipid kinases promotes cell growth and survival by generating the second messenger phosphatidylinositol… (More)
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Highly Cited
2004
Highly Cited
2004
Insulin-like growth factors elicit many responses through activation of phosphoinositide 3-OH kinase (PI3K). The tuberous… (More)
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Highly Cited
2003
Highly Cited
2003
The mechanisms that regulate the growth and survival of acute myeloid leukemia (AML) cells are largely unknown. We hypothesized… (More)
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Highly Cited
2001
Highly Cited
2001
Serum- and glucocorticoid-inducible kinases (SGKs) form a novel family of serine/threonine kinases that are activated in response… (More)
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Highly Cited
2000
Highly Cited
2000
As a dendritic cell (DC) matures, it becomes more potent as an antigen-presenting cell. This functional change is accompanied by… (More)
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Highly Cited
1997
Highly Cited
1997
Vascular endothelial growth factor (VEGF) is a regulator of vasculogenesis and angiogenesis. To investigate the role of nitric… (More)
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