Skip to search formSkip to main contentSkip to account menu

Extracellular Matrix

Known as: Intercellular matrix, ECM, Matrix, Extracellular 
The extracellular matrix is a network of fibers that hold cells together. It is found within the extracellular space and in association with the… 
National Institutes of Health

Related topics

Related topics

49 relations
ADAMTS1 protein, humanADAMTS13 protein, humanAlpha-TectorinBasement Membrane-Specific Heparan Sulfate Proteoglycan Core Protein

Broader (5)

Circular muscle layer of small intestineDense regular elastic tissueExcretory functionLoose areolar connective tissue

Narrower (2)

Intercellular matrix componentPortion of ground substance

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix
The conjunctive presence of mechanical stress and active transforming growth factor β1 (TGF-β1) is essential to convert… 
Highly Cited
2005
Highly Cited
2005
The extracellular matrix guides the orientation of the cell division axis
The cell division axis determines the future positions of daughter cells and is therefore critical for cell fate. The positioning… 
Highly Cited
2002
Highly Cited
2002
Inhibition of Transforming Growth Factor (TGF)- 1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF- Type I Receptor Kinase Activity: SB-431542
Transforming growth factor 1 (TGF1) is a potent fibrotic factor responsible for the synthesis of extracellular matrix. TGF1 acts… 
Review
1993
Review
1993
Regulation of development and differentiation by the extracellular matrix.
Differentiation is a continuously regulated process and interactions between the cell and its environment play a major role in… 
Highly Cited
1992
Highly Cited
1992
Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix
The ability of chondrocytes from calf articular cartilage to synthesize and assemble a mechanically functional cartilage‐like… 
Highly Cited
1992
Highly Cited
1992
Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo.
Development of the human embryo depends on the ability of first trimester cytotrophoblastic stem cells to differentiate and… 
Highly Cited
1991
Highly Cited
1991
Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis.
Idiopathic pulmonary fibrosis is an inexorably fatal disorder characterized by connective tissue deposition within the terminal… 
Highly Cited
1989
Highly Cited
1989
Hepatocyte function and extracellular matrix geometry: long‐term culture in a sandwich configuration
Adult rat hepatocytes cultured in a collagen sandwich system maintained normal morphology and a physiological rate of albumin… 
Highly Cited
1988
Highly Cited
1988
Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix
Transforming growth factor beta (TGF-beta) is angiogenic in vivo. In vitro, endothelial cell proliferation is inhibited by TGF… 
Review
1987
Review
1987
Cell surface receptors for extracellular matrix molecules.
Table 2 lists most of the extracellular matrix and related receptors identified to date. The wide range of binding affinities of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)