Basement Membrane-Specific Heparan Sulfate Proteoglycan Core Protein

Known as: HSPG, PLC, Perlecan 
Basement membrane-specific heparan sulfate proteoglycan core protein (4391 aa, ~469 kDa) is encoded by the human HSPG2 gene. This protein is involved… (More)

Topic mentions per year

Topic mentions per year

1970-2018
020040019702018

Papers overview

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Highly Cited
2007
Highly Cited
2007
Obesity is a serious international health problem that increases the risk of several common diseases. The genetic factors… (More)
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Highly Cited
2006
Highly Cited
2006
Angiogenesis and signaling through the RAF/mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase (MEK)/ERK… (More)
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Highly Cited
2006
Highly Cited
2006
Recent advances in stem cell biology enable us to identify cancer stem cells in solid tumors as well as putative stem cells in… (More)
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Highly Cited
2001
Highly Cited
2001
Tissue injury generates endogenous factors that heighten our sense of pain by increasing the response of sensory nerve endings to… (More)
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Highly Cited
2000
Highly Cited
2000
The roles of phosphoinositide 3-kinase (PI3K) and phospholipase C (PLC) in chemoattractant-elicited responses were studied in… (More)
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Highly Cited
1998
Highly Cited
1998
The linker molecule LAT is a critical substrate of the tyrosine kinases activated upon TCR engagement. Phosphorylated LAT binds… (More)
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Highly Cited
1991
Highly Cited
1991
We report the cloning and expression of a cDNA encoding a high molecular weight (85.2 kd) cytosolic phospholipase A2 (cPLA2) that… (More)
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Highly Cited
1990
Highly Cited
1990
Cultured bovine capillary endothelial (BCE) cells synthesize heparan sulfate proteoglycans (HSPG), which are both secreted into… (More)
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Highly Cited
1982
Highly Cited
1982
A human hepatoma cell line, HuH-7, which was established from a hepatocellular carcinoma, was found to replicate continuously in… (More)
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Highly Cited
1979
Highly Cited
1979
A significant aspect of primary hepatic carcinoma in man is the high positive correlation of hepatocellular carcinoma with… (More)
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