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Alpha-Tectorin
Known as:
Tectorin Alpha
Alpha-tectorin (2155 aa, ~240 kDa) is encoded by the human TECTA gene. This protein plays a role in hearing.
National Institutes of Health
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Related topics
Related topics
12 relations
Cell Adhesion
Cell Movement
Extracellular Matrix
Extracellular Matrix Protein Gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with α-tectorin and is mutated in autosomal dominant hearing loss (DFNA4)
Jing Zheng
,
K. K. Miller
,
+12 authors
P. Dallos
Proceedings of the National Academy of Sciences
2011
Corpus ID: 205248998
We report on a secreted protein found in mammalian cochlear outer hair cells (OHC) that is a member of the carcinoembryonic…
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2007
2007
Audioprofiling identifies TECTA and GJB2‐related deafness segregating in a single extended pedigree
NC Meyer
,
CJ Nishimura
,
S. McMordie
,
R. Smith
Clinical genetics
2007
Corpus ID: 38393510
An audioprofile displays phenotypic data from several audiograms on a single graph that share a common genotype. In this report…
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Highly Cited
2002
Highly Cited
2002
Extracellular matrices associated with the apical surfaces of sensory epithelia in the inner ear: molecular and structural diversity.
R. Goodyear
,
G. Richardson
Journal of neurobiology
2002
Corpus ID: 33435769
The ultrastructure and molecular composition of the extracellular matrices that are associated with the apical surfaces of the…
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Highly Cited
2001
Highly Cited
2001
Thyroid Hormone-deficient Period Prior to the Onset of Hearing Is Associated with Reduced Levels of β-Tectorin Protein in the Tectorial Membrane
M. Knipper
,
G. Richardson
,
+7 authors
U. Zimmermann
The Journal of Biological Chemistry
2001
Corpus ID: 23554096
The genes for α- and β-tectorin encode the major non-collagenous proteins of the tectorial membrane. Recently, a targeted…
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Highly Cited
2000
Highly Cited
2000
A Targeted Deletion in α-Tectorin Reveals that the Tectorial Membrane Is Required for the Gain and Timing of Cochlear Feedback
P. Legan
,
V. Lukashkina
,
R. Goodyear
,
M. Kössl
,
I. Russell
,
G. Richardson
Neuron
2000
Corpus ID: 17510891
Highly Cited
1999
Highly Cited
1999
An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB21.
M. Mustapha
,
D. Weil
,
+5 authors
C. Petit
Human molecular genetics
1999
Corpus ID: 38105805
In our efforts to identify new loci responsible for non-syndromic autosomal recessive forms of deafness, DFNB loci, we have…
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Highly Cited
1999
Highly Cited
1999
Tectorin mRNA expression is spatially and temporally restricted during mouse inner ear development
A. Rau
,
P. Legan
,
G. Richardson
The Journal of comparative neurology
1999
Corpus ID: 10556960
The tectorial and otolithic membranes are extracellular matrices that cover the sensory epithelia of the inner ear. They are…
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Highly Cited
1998
Highly Cited
1998
Mutations in the human alpha-tectorin gene cause autosomal dominant non-syndromic hearing impairment.
K. Verhoeven
,
L. Van Laer
,
+17 authors
G. Van Camp
Nature genetics
1998
Corpus ID: 32069001
The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory…
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1998
1998
Mapping of the alpha-tectorin gene (TECTA) to mouse chromosome 9 and human chromosome 11: a candidate for human autosomal dominant nonsyndromic deafness.
D. C. Hughes
,
P. Legan
,
K. Steel
,
G. Richardson
Genomics
1998
Corpus ID: 38885140
alpha-Tectorin is one of the major noncollagenous components of the mammalian tectorial membrane in the inner ear. We have mapped…
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Highly Cited
1997
Highly Cited
1997
The Mouse Tectorins
P. Legan
,
A. Rau
,
J. N. Keen
,
G. Richardson
The Journal of Biological Chemistry
1997
Corpus ID: 39367074
The cDNA and derived amino acid sequences for the two major non-collagenous proteins of the mouse tectorial membrane, α- and…
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