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Serine Proteinase Inhibitors

Known as: Serine Proteinase Antagonists, Serine Protease Inhibitor, Serine Protease Inhibitors 
Exogenous or endogenous compounds which inhibit SERINE ENDOPEPTIDASES.
National Institutes of Health

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Narrower (37)

3,4-dichloroisocoumarin4-(2-aminoethyl)benzenesulfonylfluoride4-(2-succinimidoethylthio)phenyl 4-guanidinobenzoateAmino Acid Chloromethyl Ketones
AngiotensinsIn BloodKAZALD1 genePancreatic Trypsin Secretory Inhibitor, Kazal

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Urinary Trypsin Inhibitor Protects against Systemic Inflammation Induced by Lipopolysaccharide
Urinary trypsin inhibitor (UTI), a serine protease inhibitor, has been widely used as a drug for patients with acute inflammatory… 
Review
2005
Review
2005
Tip of another iceberg: Drosophila serpins.
Highly Cited
2004
Highly Cited
2004
Long-range dynamic effects of point mutations propagate through side chains in the serine protease inhibitor eglin c.
Long-range interactions are fundamental to protein behaviors such as cooperativity and allostery. In an attempt to understand the… 
Highly Cited
2003
Highly Cited
2003
Serine Proteases Are Involved in the Pathogenesis of Trauma-Hemorrhagic Shock-Induced Gut and Lung Injury
The objective of this work was to test the hypothesis that intraluminal serine proteases are involved in trauma-hemorrhagic shock… 
Highly Cited
1995
Highly Cited
1995
Activation of intracellular proteases is an early event in TNF-induced apoptosis.
The serine protease inhibitor tosyl-argenine methyl ester inhibits TNF-induced apoptosis, suggesting that proteolysis is… 
Highly Cited
1995
Highly Cited
1995
A serine protease inhibitor, protease nexin I, rescues motoneurons from naturally occurring and axotomy-induced cell death.
Protease nexin I (PNI) is a member of the family of serine protease inhibitors (serpins) that have been shown to promote neurite… 
Highly Cited
1993
Highly Cited
1993
Production of alpha-1-antichymotrypsin by PSA-containing cells of human prostate epithelium.
Highly Cited
1993
Highly Cited
1993
Three-dimensional structure of soybean trypsin/chymotrypsin Bowman-Birk inhibitor in solution.
The three-dimensional structure of soybean trypsin/chymotrypsin Bowman-Birk inhibitor in solution has been determined by two… 
Highly Cited
1992
Highly Cited
1992
Proteolytic inactivation of alpha 1-proteinase inhibitor and alpha 1-antichymotrypsin by oxidatively activated human neutrophil metalloproteinases.
Highly Cited
1989
Highly Cited
1989
Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A
The rapid breakdown of target cell DNA during CTL-mediated lysis has been difficult to explain by the granule exocytosis model of… 
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