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3,4-dichloroisocoumarin

Known as: 3,4-DCL 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

CoumarinsSerine Proteinase Inhibitors

Papers overview

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Highly Cited
2011
Highly Cited
2011
Catalytic Mechanism of Rhomboid Protease GlpG Probed by 3,4-Dichloroisocoumarin and Diisopropyl Fluorophosphonate*
Background: The rhomboid protease GlpG is a prototype of the serine intramembrane protease. Results: The crystal structure of… 
2004
2004
Subsite specificities of granzyme M: a study of inhibitors and newly synthesized thiobenzyl ester substrates.
1999
1999
Purification and characterisation of a trypsin-like serine oligopeptidase from Trypanosoma congolense.
1998
1998
Structure of 3,4-dichloroisocoumarin-inhibited factor D.
Factor D (D) is a serine protease essential in the activation of the alternative complement pathway. Only a few of the common… 
1997
1997
Hydrolysis of big endothelin-1 by a serine protease in the membrane fraction of human lung
1997
1997
Degradation of vitellogenins by 170 kDa trypsin-like protease in the plasma of the tilapia, Oreochromis niloticus.
Highly Cited
1996
Highly Cited
1996
Activation of the multicatalytic endopeptidase by oxidants. Effects on enzyme structure.
It is well established that the functional properties of proteins can be compromised by oxidative damage and, in vivo, proteins… 
Highly Cited
1994
Highly Cited
1994
Proline iminopeptidase from Lactobacillus delbrueckii subsp. bulgaricus CNRZ 397: purification and characterization.
Proline iminopeptidase (PepIP) is a major peptidase in Lactobacillus delbrueckii subsp. bularicus CNRZ397, encoded by the pepIP… 
Highly Cited
1991
Highly Cited
1991
The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors.
To kill other cells, lymphocytes can exocytose granules that contain serine proteases and pore-forming proteins (perforins). We… 
1989
1989
Selective isocoumarin serine protease inhibitors block RNK-16 lymphocyte granule-mediated cytolysis.
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