H. Takano

Publications361
h-index53
Citations9,250
Highly Influential Citations326
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Diesel exhaust particles enhance antigen-induced airway inflammation and local cytokine expression in mice.
Previous experimental studies have suggested that nasal instillation of diesel exhaust particles (DEP) can enhance nasal IgE response and cytokine production. However, there is no experimental… Expand
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Effect of nanoparticles on the male reproductive system of mice.
The effects of nanoparticles toward on the male reproductive system of mice were investigated. Three sizes (14, 56 and 95 nm) of carbon black nanoparticles were intratracheally administered (0.1… Expand
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The nitric oxide hypothesis of late preconditioning
Abstract Ischemic preconditioning (PC) occurs in two phases: an early phase, which lasts 2–3 h, and a late phase, which begins 12–24 h later and lasts 3–4 days. The mechanism for the late phase of PC… Expand
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Diesel exhaust enhances allergic airway inflammation and hyperresponsiveness in mice.
We previously reported that the intratracheal instillation of diesel exhaust particles enhances allergic airway inflammation and hyperresponsiveness in mice. However, it is not known whether the… Expand
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Prenatal exposure to bisphenol A up‐regulates immune responses, including T helper 1 and T helper 2 responses, in mice
The effect of prenatal exposure to bisphenol A (BPA) on the immune system in mice was investigated. Virgin female mice were fed varying doses of BPA, on a daily basis, over a period of 18 days… Expand
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Inhalation of diesel exhaust enhances allergen-related eosinophil recruitment and airway hyperresponsiveness in mice.
We have previously shown that intratracheal instillation of suspension of diesel exhaust particles enhances allergen-related eosinophilic airway inflammation, airway hyperresponsiveness, and local… Expand
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Repeated pulmonary exposure to single-walled carbon nanotubes exacerbates allergic inflammation of the airway: Possible role of oxidative stress.
The development of nanotechnology has increased the risk of environmental exposure to types of particles other than those derived from combustion, namely, industrial nanomaterials. Patients with… Expand
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Effects of Pulmonary Exposure to Carbon Nanotubes on Lung and Systemic Inflammation with Coagulatory Disturbance Induced by Lipopolysaccharide in Mice
Despite intensive research as to the pathogenesis of lipopolysaccharide (LPS)-related inflammation with coagulatory disturbance, their exacerbating factors have not been well explored. This study… Expand
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Particulate Matter–Induced Health Effects: Who Is Susceptible?
We read with great interest a recent review by Sacks et al. (2011) and would like to add some comments to facilitating effects of particulate matter (PM) on preexisting respiratory diseases. First of… Expand
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Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model.
The development of nanotechnology has increased the risk of exposure to types of particles other than combustion-derived particles in the environment, namely, industrial nanomaterials. On the other… Expand
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