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Amino Acid Chloromethyl Ketones

Known as: Peptide Chloromethyl Ketones, Chloromethyl Ketones, Peptide, Amino Acid Chloromethyl Ketones [Chemical/Ingredient] 
Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The synthesis of indenols and fulvenes was achieved through Rh-catalyzed C-H bond activation of simple and diverse aryl ketone… Expand
Review
2010
Review
2010
10.2. Synthesis of Other -Amino Acid Derivatives 3676 10.2.1. Synthesis of -Amino Ketones 3676 10.2.2. Synthesis of -Amino… Expand
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Review
2008
Review
2008
2.6.4. Other Carbohydrate-Based Catalysts 3976 2.7. Carbocyclic Ketones 3977 2.8. Ketones with an Attached Chiral Moiety 3979 3… Expand
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Review
2007
Review
2007
  • Yi Jin, T. Penning
  • Annual review of pharmacology and toxicology
  • 2007
  • Corpus ID: 11863237
Aldo-keto reductases (AKRs) are soluble NAD(P)(H) oxidoreductases that primarily reduce aldehydes and ketones to primary and… Expand
Highly Cited
2006
Highly Cited
2006
  • Yuhua Zhang, C. Li
  • Journal of the American Chemical Society
  • 2006
  • Corpus ID: 19934783
A direct Cross-Dehydrogenative-Coupling (CDC) between benzyl ethers and simple ketones was developed without using any metal… Expand
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Highly Cited
2005
Highly Cited
2005
  • R. Moriarty
  • The Journal of organic chemistry
  • 2005
  • Corpus ID: 37773050
The synthetic utility of organohypervalent iodine reagents will be illustrated by their use in the alpha-hydroxydimethylacetal… Expand
Highly Cited
1999
Highly Cited
1999
The amyloid beta-protein (Abeta), implicated in the pathogenesis of Alzheimer's disease (AD), is a proteolytic metabolite… Expand
Highly Cited
1995
Highly Cited
1995
A novel Ca-independent phospholipase A2 (PLA2) has recently been purified from the murine macrophage-like cell line P388D1… Expand
Highly Cited
1994
Highly Cited
1994
Interleukin-1 beta converting enzyme (ICE) is a cysteine protease in monocytes that is essential for the proteolytic activation… Expand
Highly Cited
1985
Highly Cited
1985
The use of fluoro ketones as inhibitors of hydrolytic enzymes has been investigated. The acetylcholine analogues 6,6-dimethyl-1,1… Expand