Pancreatic Trypsin Secretory Inhibitor, Kazal

Known as: Pancreatic Secretory Trypsin Inhibitor, Kazal, TATI, SPINK1 
Pancreatic secretory trypsin inhibitor (79 aa, ~9 kDa) is encoded by the human SPINK1 gene. This protein plays a role in the modulation of trypsin… (More)
National Institutes of Health

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Highly Cited
2017
Highly Cited
2017
Table 1 lists the causes of acute pancreatitis. Gallstones are the most common cause.1,2 Migrating gallstones cause transient… (More)
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2009
2009
Serine protease inhibitor, Kazal type 1 (SPINK1) is expressed not only in normal human pancreatic acinar cells but also in a… (More)
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Review
2006
Review
2006
Trypsin activity is properly suppressed in the pancreatic acinar cells under normal conditions. A small amount of trypsinogen is… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND & AIMS Serine protease inhibitor Kazal type 1 (SPINK1), which is structurally similar to epidermal growth factor, is… (More)
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2005
2005
OBJECTIVES Mutations in the secretory trypsin inhibitor (SPINK1) gene have been found to be associated with hereditary and… (More)
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Highly Cited
1991
Highly Cited
1991
Data from various laboratories have indicated associations of various alleles determined by RFLPs within or adjacent to several… (More)
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Highly Cited
1989
Highly Cited
1989
A lacZ gene without a promoter, but containing its ribosome-binding site, was cloned next to the kanamycin-resistance (KmR) gene… (More)
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1989
1989
Arg-42 or Lys-43 or Arg-44 of human pancreatic secretory trypsin inhibitor (PSTI) was replaced by Thr or Ser by site-directed… (More)
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1987
1987
The human pancreatic secretory trypsin inhibitor (PSTI) gene was isolated from a human gene library. Restriction endonuclease… (More)
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1986
1986
Normal and metaplastic gastrointestinal mucosa obtained at surgical resection were studied by light microscopy, using the… (More)
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