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HIV Protease Inhibitors

Known as: Inhibitors, HIV Protease, HIV Protease Inhibitor, Protease Inhibitors, HIV 
A protease inhibitor that is designed to target the human immunodeficiency virus (HIV) protease while sparing other host cell proteases. HIV protease… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Conflicting drug-drug interaction (DDI) studies with the HIV protease inhibitors (PIs) suggest net induction or inhibition of… Expand
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Highly Cited
2010
Highly Cited
2010
The effects of human immunodeficiency virus (HIV) protease inhibitors (PI) on the accumulation of the fluorescent bile salt… Expand
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Highly Cited
2007
Highly Cited
2007
PURPOSE The development of new cancer drugs is slow and costly. HIV protease inhibitors are Food and Drug Administration approved… Expand
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Highly Cited
2007
Highly Cited
2007
HIV protease inhibitors (HIV-PIs) target the HIV aspartyl protease, which cleaves the HIV gag-pol polyprotein into shorter… Expand
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Highly Cited
2005
Highly Cited
2005
Several human immunodeficiency virus (HIV) protease inhibitors, including atazanavir, indinavir, lopinavir, nelfinavir, ritonavir… Expand
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Highly Cited
2005
Highly Cited
2005
Human immunodeficiency virus (HIV) protease inhibitors (PIs) are inhibitors of CYP3A enzymes, but the mechanism is poorly defined… Expand
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Highly Cited
2000
Highly Cited
2000
Retroviral protease inhibitors used as therapy for HIV-1 infection have been causally associated with serious metabolic side… Expand
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Highly Cited
2000
Highly Cited
2000
HIV protease inhibitors have proven remarkably effective in treating HIV-1 infection. However, some tissues such as the brain and… Expand
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Highly Cited
1997
Highly Cited
1997
Coadministration with the human immunodeficiency virus (HIV) protease inhibitor ritonavir was investigated as a method for… Expand
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Highly Cited
1994
Highly Cited
1994
Mechanistic information and structure-based design methods have been used to design a series of nonpeptide cyclic ureas that are… Expand
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