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HIV Protease Inhibitors

Known as: Inhibitors, HIV Protease, HIV Protease Inhibitor, Protease Inhibitors, HIV 
A protease inhibitor that is designed to target the human immunodeficiency virus (HIV) protease while sparing other host cell proteases. HIV protease… 
National Institutes of Health

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Narrower (14)

Abbott 77003AmprenavirAtazanavir sulfateDMP 323
Antiviral AgentsHIV Protease Inhibitors [MoA]Human Immunodeficiency Virus Protease Inhibitor [EPC]In Blood

Broader (1)

Protease Inhibitors

Papers overview

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2016
2016
Abstracts from the 14th International Symposium on NeuroVirology October 25–28, 2016, Toronto, Ontario, Canada
2016
2016
HIV Protease Inhibitors Apoptotic Effect in SH-SY 5 Y Neuronal Cell Line
Background: Prophylactic treatment regimens to prevent mother-to-child HIV transmission include protease inhibitors Lopinavir and… 
2013
2013
Title : Potent HIV protease inhibitors containing a novel ( hydroxyethyl ) amide isostere
Quinoline-2-carbohydrazide (3) was reacted with aryl or alkyl isothiocyanates to give the corresponding quinoline… 
2012
2012
a-Dehydro B-amino acid derivatives as turn inducer: Synthesis of potential HIV protease inhibitors based on structural mimicr/
The ~and y-turn conformations in proteins have been shown 1 to play important roles during the biochemical recognition process… 
2002
2002
Antiapoptotic activity by HIV protease inhibitors either alone or boostered.
2001
2001
Structure-Based Design of Achiral , Nonpeptidic Hydroxybenzamide as a Novel P 2 / P 2 ' Replacement for the Symmetry-Based HIV Protease Inhibitors
-A combination of structure-activity studies, kinetic analysis, X-ray crystallographic analysis, and modeling were employed in… 
2000
2000
Identifying and Characterizing HIV Protease Inhibitors.
HIV protease catalyzes the hydrolysis of specific peptide bonds of viral polyproteins, thus processing these polyproteins into… 
1999
1999
Rational Drug Design Approach to Synthesizing HIV-1 Protease Inhibitors
Introduction Human Immunodeficiency Virus (HIV), the causitive agent of AIDS, now infects an estimated 20 million people… 
1994
1994
Nonpeptide HIV Protease Inhibitors. Differential Introduction of Alkylamino Groups into the Two Aryl Rings of Haloperidol
In efforts to synthesize haloperidol analogues with improved properties as HIV protease inhibitors, methods were sought to… 
Review
1994
Review
1994
Protease inhibitors--an update.
After five years of highly competitive work by pharmaceutical companies, a new class of drugs, called protease inhibitors, has…