HIV Protease Inhibitors

Known as: Inhibitors, HIV Protease, HIV Protease Inhibitor, Protease Inhibitors, HIV 
A protease inhibitor that is designed to target the human immunodeficiency virus (HIV) protease while sparing other host cell proteases. HIV protease… (More)

Topic mentions per year

Topic mentions per year

1990-2018
020406019902018

Papers overview

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Highly Cited
2007
Highly Cited
2007
PURPOSE The development of new cancer drugs is slow and costly. HIV protease inhibitors are Food and Drug Administration approved… (More)
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2005
2005
The proteasomes of some protozoa are possible targets for chemotherapy. Leishmaniasis is a major health problem in human… (More)
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Highly Cited
2002
Highly Cited
2002
Treatment with HIV-1 protease inhibitors (PI) is associated with a reduced incidence or regression of Kaposi sarcoma (KS). Here… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Poor adherence to HIV protease inhibitors may compromise the effectiveness of treatment. Few studies have compared… (More)
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Highly Cited
2000
Highly Cited
2000
Retroviral protease inhibitors used as therapy for HIV-1 infection have been causally associated with serious metabolic side… (More)
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Highly Cited
2000
Highly Cited
2000
HIV protease inhibitors have proven remarkably effective in treating HIV-1 infection. However, some tissues such as the brain and… (More)
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2000
2000
Hyperlipidemia may complicate the use of HIV protease inhibitors (PIs) in AIDS therapy. To determine the cause of hyperlipidemia… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Progressive subcutaneous fat wasting, fat accumulation, dyslipidaemia and insulin resistance in HIV-infected patients… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To describe a syndrome of peripheral lipodystrophy (fat wasting of the face, limbs and upper trunk), hyperlipidaemia… (More)
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Highly Cited
1997
Highly Cited
1997
Coadministration with the human immunodeficiency virus (HIV) protease inhibitor ritonavir was investigated as a method for… (More)
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