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NFKBIA wt Allele

Known as: NFKBI, Nuclear Factor of Kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, Alpha wt Allele, MAD3 
Human NFKBIA wild type allele is located in the vicinity of 14q13 and is approximately 3 kb in length. This allele, which encodes NF-kappa-B… 
National Institutes of Health

Related topics

Related topics

37 relations
14q13AKT Signaling PathwayATM Signaling PathwayAdipocytokine Signaling Pathway

Broader (1)

NFKBIA gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway
The RNA-binding protein RC3H1 (also known as ROQUIN) promotes TNFα mRNA decay via a 3′UTR constitutive decay element (CDE). Here… 
2015
2015
Sources of dynamic variability in NF-κB signal transduction: A mechanistic model
The transcription factor NF-κB (p65/p50) plays a central role in the coordination of cellular responses by activating the… 
Highly Cited
2006
Highly Cited
2006
Cocoa polyphenols inhibit phorbol ester-induced superoxide anion formation in cultured HL-60 cells and expression of cyclooxygenase-2 and activation of NF-kappaB and MAPKs in mouse skin in vivo.
We investigated the antioxidant and antiinflammatory activities of a flavonoid-rich polyphenolic fraction of cocoa. Cocoa… 
2005
2005
Up-regulation of CXCR 4 Expression in PC-3 Cells by Stromal-Derived Factor-1 A ( CXCL 12 ) Increases Endothelial Adhesion and Transendothelial Migration : Role of MEK / ERK Signaling Pathway…
The chemokine stromal-derived factor-1A (SDF-1A/CXCL-12) and its receptor, CXCR4, play a crucial role in adhesion and… 
Highly Cited
2001
Highly Cited
2001
Early activation of IKKβ during in vivo myocardial ischemia
We have demonstrated that in vitro brief ischemia activates nuclear factor (NF)-kappaB in rat myocardium. We report in vivo… 
2001
2001
S-phase-specific expression of the Mad3 gene in proliferating and differentiating cells.
The Myc/Max/Mad transcription factor network plays a central role in the control of cellular proliferation, differentiation and… 
1999
1999
Structural analysis, expression, and chromosomal localization of the mouse ikba gene
Abstract The pleiotropic transcription factor NF-κB is localized in the cytoplasm bound to its inhibitory subunit IκB. The… 
Highly Cited
1998
Highly Cited
1998
HTLV-I Tax Protein Binds to MEKK1 to Stimulate IκB Kinase Activity and NF-κB Activation
Highly Cited
1997
Highly Cited
1997
IκB kinase: Beginning, not the end
It is not often that a problem in biology is so well defined and yet so elusive. Just a decade ago, David Baltimore and… 
1997
1997
Distinct Functional Properties of IkBa and IkBb
The biological activity of the transcription factor NF-kB is controlled mainly by the IkBa and IkBb proteins, which restrict NF… 
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