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- Publications
- Influence
Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced…
- G. Messer, U. Spengler, +5 authors E. Weiss
- Biology, Medicine
- The Journal of experimental medicine
- 1 January 1991
Since a dysregulated synthesis of tumor necrosis factor alpha (TNF- alpha) may be involved in the pathogenesis of autoimmune diseases, it was of interest to precisely locate the recently reported… Expand
NF-kappaB and AP-1 are responsible for inducibility of the IL-6 promoter by ionizing radiation in HeLa cells.
- A. Beetz, R. Peter, +6 authors G. Messer
- Biology, Medicine
- International journal of radiation biology
- 2000
PURPOSE
To investigate the mechanisms leading to initiation by ionizing radiation of IL-6 transcription in HeLa cells.
MATERIALS AND METHODS
HeLa cells were irradiated with X-rays at a dose rate of… Expand
Structural characteristics of the 5' region of the human ICAM-1 gene.
- B. G. Stade, G. Messer, G. Riethmueller, J. Johnson
- Biology, Medicine
- Immunobiology
- 1 December 1990
The ICAM-1 glycoprotein, one of the major cellular adhesion molecules, exhibits a diverse and highly regulated tissue distribution. To better understand the regulatory mechanisms underlying its… Expand
Clinical and immunologic parameters during thalidomide treatment of lupus erythematosus
- M. Walchner, M. Meurer, G. Plewig, G. Messer
- Medicine
- International journal of dermatology
- 1 May 2000
Background Thalidomide is used as an experimental drug for the treatment of chronic inflammatory diseases with an autoimmune or infectious background. The pharmacologic action involves the… Expand
Strong and prolonged induction of c-jun and c-fos proto-oncogenes by photodynamic therapy.
- G. Kick, G. Messer, G. Plewig, Peter Kind, A. Goetz
- Biology, Medicine
- British Journal of Cancer
- 1 July 1996
Photodynamic therapy (PDT) is currently under investigation in phase II and III clinical studies for the treatment of tumours in superficial localisations. Thus far, the underlying mechanisms of PDT… Expand
Autoantibody Detection Using Indirect Immunofluorescence on HEp‐2 Cells
- U. Sack, K. Conrad, +8 authors R. Mierau
- Medicine
- Annals of the New York Academy of Sciences
- 1 September 2009
The detection of autoantibodies is an important element in the diagnosis and monitoring of disease progression in patients with autoimmune diseases. In laboratory diagnostic tests for connective… Expand
IgG1 and IgG3 are the major immunoglobulin subclasses targeting epitopes within the NC16A domain of BP180 in pemphigoid gestationis.
- I. Chimanovitch, E. Schmidt, +5 authors D. Zillikens
- Medicine
- The Journal of investigative dermatology
- 1 July 1999
Cloning and genomic characterization of LST1: a new gene in the human TNF region
- I. Holzinger, A. D. Baey, G. Messer, G. Kick, H. Zwierzina, E. Weiss
- Biology, Medicine
- Immunogenetics
- 2004
The leucocyte specific transcript — 1 (LST1) represents the human homolog of the mouse B144 transcript, encoded within the tumor necrosis factor (TNF) region of the human major histocompatibility… Expand
Tumor necrosis factor beta (TNF-beta) induces binding of the NF-kappa B transcription factor to a high-affinity kappa B element in the TNF-beta promoter.
- G. Messer, E. H. Weiss, P. Baeuerle
- Medicine
- Cytokine
- 1990
The expression of the gene encoding tumor necrosis factor beta (TNF-beta) (lymphotoxin) is induced in T cells by various extracellular stimuli. We noticed that most such stimuli also activate the… Expand
Cicatricial pemphigoid: IgA and IgG autoantibodies target epitopes on both intra‐ and extracellular domains of bullous pemphigoid antigen 180
- E. Schmidt, C. Skrobek, +5 authors D. Zillikens
- Chemistry, Medicine
- The British journal of dermatology
- 1 November 2001
Background Cicatricial pemphigoid (CP) is an autoimmune subepidermal blistering disease where autoantibodies target various components of the dermal–epidermal junction, including the bullous… Expand