H. Lee

Publications300
h-index54
Citations9,892
Highly Influential Citations370
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Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals.
To express the antioxidant capacity of plant foods in a more familiar and easily understood manner (equivalent to vitamin C mg/100 g), two stable radical species, ABTS(*)(-) and DPPH(*), commonly… Expand
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Major phenolics in apple and their contribution to the total antioxidant capacity.
The contribution of each phytochemical to the total antioxidant capacity of apples was determined. Major phenolic phytochemicals of six apple cultivars were identified and quantified, and their… Expand
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Cocoa has more phenolic phytochemicals and a higher antioxidant capacity than teas and red wine.
Black tea, green tea, red wine, and cocoa are high in phenolic phytochemicals, among which theaflavin, epigallocatechin gallate, resveratrol, and procyanidin, respectively, have been extensively… Expand
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Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine.
Considerable attention has focused on the health-promoting effects of red wine and its nonflavonoid polyphenol compound resveratrol. However, the underlying molecular mechanisms and molecular… Expand
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Subunit composition determines picrotoxin and bicuculline sensitivity of Drosophila gamma-aminobutyric acid receptors.
Few gamma-aminobutyric acid (GABA) receptor subunits have been cloned from insects. These include Resistance to dieldrin, or Rdl, and a homologue of the vertebrate GABAA receptor beta subunit. Unlike… Expand
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Transient receptor potential vanilloid type‐1 channel regulates diet‐induced obesity, insulin resistance, and leptin resistance
  • E. Lee, D. Y. Jung, +11 authors J. Kim
  • Biology, Medicine
  • FASEB journal : official publication of the…
  • 17 April 2015
Insulin resistance is a major characteristic of obesity and type 2 diabetes, but the underlying mechanism is unclear. Recent studies have shown a metabolic role of capsaicin that may be mediated via… Expand
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Luteolin inhibits protein kinase C(epsilon) and c-Src activities and UVB-induced skin cancer.
Luteolin, a flavonoid present in various vegetables including onion and broccoli, has been reported to possess anticarcinogenic effects. However, its chemopreventive effect on UV-induced skin cancer… Expand
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The roles of polyphenols in cancer chemoprevention
Oxidative stress imposed by reactive oxygen species (ROS) plays a crucial role in the pathophysiology associated with neoplasia, atherosclerosis, and neurodegenerative diseases. The ROS‐induced… Expand
  • 166
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Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis.
Multiple lines of evidences suggest that oxidative stress induced by reactive oxygen species are closely related to multi-stage carcinogenesis. Polyphenols, a group of chemicals with more than one… Expand
  • 141
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Phosphoinositide 3-kinase is a novel target of piceatannol for inhibiting PDGF-BB-induced proliferation and migration in human aortic smooth muscle cells.
AIMS Abnormal migration and proliferation of human aortic smooth muscle cells (HASMCs) to the intima causes intimal thickening of the aorta, which is strongly related to the development of… Expand
  • 78
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