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NFKBIA gene

Known as: IKBA, NUCLEAR FACTOR OF KAPPA LIGHT CHAIN GENE ENHANCER IN B CELLS INHIBITOR, NFKBIA 
This gene plays a role in signal transduction and transcriptional activation of target genes. It is also involved in the inhibition of apoptosis.
National Institutes of Health

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Related topics

10 relations
ApoptosisI-kappa B ProteinsNF-kappaB inhibitor alphaNFKBIA protein, human

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NFKBIA wt Allele

Papers overview

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2012
2012
Transcriptomic analysis of the effect of ifosfamide on MDCK cells cultivated in microfluidic biochips.
2008
2008
IκB kinase β inhibition induces cell death in Imatinib-resistant and T315I Dasatinib-resistant BCR-ABL+ cells
Chronic myelogenous leukemia is a malignant disease of the hematopoietic stem cell compartment, which is characterized by… 
2006
2006
beta cell cytoprotective strategies: establishing the relative roles for iNOS and ROS.
2005
2005
Germline mutations and polymorphisms in the NFKBIA gene in Hodgkin lymphoma
Somatic inactivation of NFKBIA, the gene encoding IκBα, is a frequent occurrence in the malignant Hodgkin and Reed‐Sternberg (HRS… 
2004
2004
Regulation of Vinca alkaloid-induced apoptosis by NF-κB/IκB pathway in human tumor cells
Antimicrotubule Vinca alkaloids, such as vinblastine and vincristine, interfere with the dynamics of microtubules and have… 
2003
2003
Identification of variants in NFKBIA and association analysis with hepatocellular carcinoma risk among chronic HBV patients
Human nuclear factor of kappa light chain gene enhancer in B cells inhibitor, alpha (NFKBIA) inhibits the action of NF‐κB by… 
2002
2002
Inducible Nitric Oxide Synthase Is Not Required in the Development of Endotoxin Tolerance in Mice
We investigated the role of inducible nitric oxide synthase (iNOS) in endotoxin tolerance, which was induced in mice genetically… 
Highly Cited
2002
Highly Cited
2002
Inhibition of TNF-alpha and IL-6 production by Aucubin through blockade of NF-kappaB activation RBL-2H3 mast cells.
Antigen (Ag)-stimulated mast cells induce synthesis and production of cytokines including tumor necrosis factor (TNF)-alpha and… 
2001
2001
Induction of the ubiquitin-proteasome pathway during the keratocyte transition to the repair fibroblast phenotype.
PURPOSE To examine dynamics and function of the ubiquitin (Ub)-proteasome pathway (UPP) during corneal stromal cell acquisition… 
2001
2001
Escherichia coli Enterotoxin B Subunit Triggers Apoptosis of CD8+ T Cells by Activating Transcription Factor c-Myc
ABSTRACT Heat-labile enterotoxin from enterotoxinogenic Escherichia coli is not only an important cause of diarrhea in humans and… 
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