NFKBIA protein, human

Known as: NF-Kappa B Inhibitor Alpha, IKBA, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha protein, human 
NF-kappa-B inhibitor alpha (317 aa, ~36 kDa) is encoded by the human NFKBIA gene. This protein is involved in the cytoplasmic localization of the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Inflammation and innate immunity involve signalling pathways leading to the production of inflammatory mediators. Usually such… (More)
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Highly Cited
2005
Highly Cited
2005
The association of the NF-kappaB p65/p50 dimer with IkappaBalpha plays a pivotal role in regulating its nuclear translocation and… (More)
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Highly Cited
2004
Highly Cited
2004
Apoptosis induced by p53 has been proposed to involve activation of the transcription factor NF-kappaB. Here we describe the… (More)
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Highly Cited
2004
Highly Cited
2004
Previous studies have suggested more than 20 genetic intervals that are associated with susceptibility to type 1 diabetes (T1D… (More)
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Highly Cited
2002
Highly Cited
2002
We aimed to investigate the dynamics of the NF-kappaB signaling pathway in living cells using GFP variants of p65-NF-kappaB… (More)
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Highly Cited
2001
Highly Cited
2001
Gene expression profiling has revealed that diffuse large B cell lymphoma (DLBCL) consists of at least two distinct diseases… (More)
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Highly Cited
2000
Highly Cited
2000
Regulation of NF-kappaB occurs through phosphorylation-dependent ubiquitination of IkappaBalpha, which is degraded by the 26S… (More)
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Highly Cited
1998
Highly Cited
1998
Activation of NF-kappaB is achieved by ubiquitination and proteasome-mediated degradation of IkappaBalpha. We have detected… (More)
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Highly Cited
1998
Highly Cited
1998
Selected clones of the sympathetic precursor-like cell line PC12 (rCl8) are resistant to oxidative cell death induced by the… (More)
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Highly Cited
1996
Highly Cited
1996
Signal-induced activation of the transcription factor NF-kappaB requires specific phosphorylation of the inhibitor IkappaBalpha… (More)
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