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NF-kappaB inhibitor alpha

Known as: alpha, NF-KappaB Inhibitor, NF KappaB Inhibitor alpha, I Kappa B-alpha Protein 
An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes, sequesters transcription factor NF-kappaB as an inactive… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Human mantle cell lymphoma (MCL), an aggressive B cell non-Hodgkin's lymphoma, is characterized by the overexpression of cyclin… Expand
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Highly Cited
2003
Highly Cited
2003
The transcription factor NF-kappaB is activated by the degradation of its inhibitor IkappaBalpha, resulting in its nuclear… Expand
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Highly Cited
2002
Highly Cited
2002
Nuclear localization of the transcriptional activator NF-kappaB (nuclear factor kappaB) is controlled in mammalian cells by three… Expand
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Highly Cited
2002
Highly Cited
2002
We have shown that thalidomide (Thal) and its immunomodulatory derivatives (IMiDs), proteasome inhibitor PS-341, and As(2)O(3… Expand
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Highly Cited
2001
Highly Cited
2001
The nuclear expression and action of the nuclear factor kappa B (NF-kappaB) transcription factor requires signal-coupled… Expand
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Highly Cited
2001
Highly Cited
2001
Activation of the transcription factor nuclear factor-kappaB (NF-kappaB) has been suggested to participate in chronic disorders… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND & AIMS The transcription factor nuclear factor-kappaB (NF-kappaB) plays a central role in regulating immune and… Expand
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Highly Cited
1998
Highly Cited
1998
Activation of NF-kappaB is achieved by ubiquitination and proteasome-mediated degradation of IkappaBalpha. We have detected… Expand
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Highly Cited
1998
Highly Cited
1998
We examined the mechanisms by which two different types of photonic radiation, short wavelength UV (UV-C) and gamma radiation… Expand
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Highly Cited
1998
Highly Cited
1998
IkappaBalpha regulates the transcription factor NF-kappaB through the formation of stable IkappaBalpha/NF-kappaB complexes. Prior… Expand
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