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Minor Groove
The smaller of the two types of spiral grooves found on a right-handed DNA double helix; located between the sugar phosphate backbones of two DNA…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Design and synthesis of novel thiazole-containing cross-linked polyamides related to the antiviral antibiotic distamycin.
Sanjay K. Sharma
,
M. Tandon
,
J. Lown
Journal of Organic Chemistry
2000
Corpus ID: 24525205
A family of naturally occurring oligopeptides includes netropsin, distamycin, anthelvencin, kikumycin B, amidinomycin, and…
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1998
1998
DNA recognition: Reading the minor groove
C. Hélène
Nature
1998
Corpus ID: 29305856
One aim in drug development is to design molecules that recognize and bind to specific sequences of the DNA double helix, and can…
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Highly Cited
1989
Highly Cited
1989
Solution structure of the chromomycin-DNA complex.
X. Gao
,
D. Patel
Biochemistry
1989
Corpus ID: 22679584
The structure of the chromomycin-DNA complex at the deoxyoctanucleotide duplex level has been determined from one- and two…
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Highly Cited
1986
Highly Cited
1986
Solution structure of [d(A-T)5]2 via complete relaxation matrix analysis of two-dimensional nuclear Overhauser effect spectra and molecular mechanics calculations: evidence for a hydration tunnel.
E. Suzuki
,
N. Pattabiraman
,
G. Zon
,
T. James
Biochemistry
1986
Corpus ID: 23919107
Pure absorption phase proton two-dimensional nuclear Overhauser effect (2D NOE) spectra at 500 MHz have been obtained for [d(5…
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1986
1986
Cationic porphyrins as probes of DNA structure.
S. D. Bromley
,
B. Ward
,
J. Dabrowiak
Nucleic Acids Research
1986
Corpus ID: 39830968
The DNA binding specificity of a group of cationic manganese porphyrin complexes has been examined using DNase I footprinting…
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1986
1986
Sequence-dependent recognition of DNA duplexes. Netropsin complexation to the AATT site of the d(G-G-A-A-T-T-C-C) duplex in aqueous solution.
D. Patel
,
L. Shapiro
Journal of Biological Chemistry
1986
Corpus ID: 34336647
We have investigated intermolecular interactions and conformational features of the netropsin X d(G-G-A-A-T-T-C-C) complex by one…
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1985
1985
Mode of reversible binding of neocarzinostatin chromophore to DNA: evidence for binding via the minor groove.
D. Dasgupta
,
I. Goldberg
Biochemistry
1985
Corpus ID: 7764097
Two general approaches have been taken to understand the mechanism of the reversible binding of the nonprotein chromophore of…
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1979
1979
Netropsin . dG-dG-dA-dA-dT-dT-dC-dC complex. Antibiotic binding at adenine . thymine base pairs in the minor groove of the self-complementary octanucleotide duplex.
D. Patel
European Journal of Biochemistry
1979
Corpus ID: 26688303
The structure of the netropsin . dG-dG-dA-dA-dT-dT-dC-dC complex (one antibiotic molecule/self-complementary octanucleodide…
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1978
1978
A study of unwinding of DNA and shielding of the DNA grooves by RNA polymerase by using methylation with dimethylsulphate.
A. F. Melnikova
,
R. Beabealashvilli
,
A. Mirzabekov
European Journal of Biochemistry
1978
Corpus ID: 25786947
The dimethylsulphate method has been used to study the complexes of RNA polymerase (Escherichia coli) with DNA of T7 phage, poly…
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1974
1974
Localization of chromatin proteins within DNA grooves by methylation of chromatin with dimethyl sulphate
A. Mirzabekov
,
A. F. Melnikova
Molecular Biology Reports
1974
Corpus ID: 21514893
The use of the comparative modification with 3H-dimethyl sulphate (DMS) of free DNA and DNA in different complexes is proposed to…
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