Minor Groove

The smaller of the two types of spiral grooves found on a right-handed DNA double helix; located between the sugar phosphate backbones of two DNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1964-2018
05010015019642018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Sequence-dependent recognition of dsDNA-binding proteins is well understood, yet sequence-specific recognition of dsRNA by… (More)
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Highly Cited
2010
Highly Cited
2010
The bacterial nucleoid-associated protein Fis regulates diverse reactions by bending DNA and through DNA-dependent interactions… (More)
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Highly Cited
1999
Highly Cited
1999
The ecteinascidins (Ets), which are natural products derived from marine tunicates, exhibit potent antitumor activity. Of the… (More)
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Highly Cited
1998
Highly Cited
1998
The design of synthetic ligands that read the information stored in the DNA double helix has been a long-standing goal at the… (More)
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Highly Cited
1997
Highly Cited
1997
The tripeptide 1,2-dihydro-(3H)-pyrrolo[3,2-e]indole-7-carboxylate (CDPI3) binds to the minor groove of DNA with high affinity… (More)
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Highly Cited
1997
Highly Cited
1997
The solution structure of a complex between a truncated form of HMG-I(Y), consisting of the second and third DNA binding domains… (More)
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Highly Cited
1996
Highly Cited
1996
Ecteinascidin 743 is one of several related marine alkaloids isolated from the Caribbean tunicate Ecteinascidia turbinata. It is… (More)
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Highly Cited
1994
Highly Cited
1994
The three-dimensional structure of a ternary complex of the purine repressor, PurR, bound to both its corepressor, hypoxanthine… (More)
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Highly Cited
1994
Highly Cited
1994
Chromatin in eukaryotic nuclei is thought to be partitioned into functional loop domains that are generated by the binding of… (More)
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Highly Cited
1993
Highly Cited
1993
The three-dimensional structure of a TATA-box binding polypeptide complexed with the TATA element of the adenovirus major late… (More)
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