Analysis of local helix bending in crystal structures of DNA oligonucleotides and DNA-protein complexes.

@article{Young1995AnalysisOL,
  title={Analysis of local helix bending in crystal structures of DNA oligonucleotides and DNA-protein complexes.},
  author={Matthew A. Young and G. Ravishanker and David L. Beveridge and Helen M. Berman},
  journal={Biophysical journal},
  year={1995},
  volume={68 6},
  pages={
          2454-68
        }
}
Sequence-dependent bending of the helical axes in 112 oligonucleotide duplex crystal structures resident in the Nucleic Acid Database have been analyzed and compared with the use of bending dials, a computer graphics tool. Our analysis includes structures of both A and B forms of DNA and considers both uncomplexed forms of the double helix as well as those bound to drugs and proteins. The patterns in bending preferences in the crystal structures are analyzed by base pair steps, and emerging… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 119 references

" . . . the Tyranny of the Lattice . . . "

K. Grzeskowiak, M. Grzeskowiak, G. G. Prive, J. Quintana, P. Schultze
Proc . Natl . Acad . Sci . USA . • 1994

Analysis of helix bending in crystal structures and molecular dynamics simulations of DNA oligonucleotides

R. H. Sarma, M. H. Sarma, R. E. Dickerson
Structural Biology : The State of the Art . Proceedings of the 8 th Conversation . • 1994

Base pair roll and tilt in B - DNA bending

M. H. Sarma
Structural Biology : The State of the Art , Proceedings of the Eighth Conversation • 1994

Modelling DNA

R. Lavery, B. Hartmann
1994

Crystal structure

Jenkins, S. Neidle
1993