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Metal-induced toxicity and carcinogenicity, with an emphasis on the generation and role of reactive oxygen and nitrogen species… Expand The Ames Salmonella/microsome mutagenicity assay (Salmonella test; Ames test) is a short-term bacterial reverse mutation assay… Expand Interindividual variations in the level and activity of cytochrome P-450 enzymes were investigated in the liver microsomes of 30… Expand A yeast cytosol is shown to contain two distinct activities that stimulate protein translocation across microsomal membranes. One… Expand We describe in this paper the general methods for using the Salmonella/microsome test as a mutagenesis screening system. The… Expand About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple… Expand The data presented in this paper demonstrate that native small ribosomal subunits from reticulocytes (containing initiation… Expand The presence in mammalian liver microsomes of a carbon monoxide-binding pigment has been reported by Klingenberg (1) and by… Expand The presence in mammalian liver microsomes of a carbon monoxide-binding pigment has been reported by Klingenberg (1) and by… Expand 8. HEPPEL, L. A., in S. P. COLOWICK AND N. 0. KAPLAN (Editors), Methods in enzymology, Vol. II, Academic Press, Inc., New York… Expand