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Microsomes

Known as: Endoplasmic reticulum vesicle, Microsome 
Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are… 
National Institutes of Health

Related topics

Related topics

12 relations
Cytochrome P450Endoplasmic ReticulumGolgi ApparatusMicrobiological

Broader (2)

Intracellular MembranesOrganelles

Narrower (1)

Microsomes, Liver

Papers overview

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Highly Cited
1986
Highly Cited
1986
Comparison of cytochrome P-450 content and activities in liver microsomes of seven animal species, including man.
The cytochrome P-450 content found in human livers obtained post mortem was between 0.21-0.42 nmol/mg protein. The kinetic… 
Highly Cited
1982
Highly Cited
1982
Multiplicity strain differences, and topology of phenobarbital-induced cytochromes P-450 in rat liver microsomes.
The multiplicity of phenobarbital-induced cytochromes P-450 in live microsomes from male rats was investigated by using two… 
Highly Cited
1982
Highly Cited
1982
The nature of nitrosamine denitrosation by rat liver microsomes.
The nature of the denitrosation of nitrosamines by rat liver microsomes was investigated. The rates of NADPH-dependent… 
1979
1979
Comparative metabolism of 2-[bis(2-chloroethyl)amino]tetrahydro-2-H-1,3,2-oxazaphosphorine-2-oxide (cyclophosphamide) and its enantiomers in humans.
The comparative metabolism of the enantiomers of cyclo phosphamide and of the racemate has been studied in humans. Four patients… 
Highly Cited
1978
Highly Cited
1978
Reduced nicotinamide adenine dinucleotide phosphate-dependent formation of 2,3-dihydro-2,3-dihydroxyaflatoxin B1 from aflatoxin B1 by hepatic microsomes.
2,3-Dihydro-2,3-dihydroxyaflatoxin B1 (dihydrodiol) was formed as a major metabolite in the incubation of aflatoxin B1 with rat… 
Highly Cited
1977
Highly Cited
1977
Effect of dietary fat saturation on acylcoenzyme A:-cholesterol acyltransferase activity of Ehrlich cell microsomes.
Ehrlich cells grown in mice fed coconut oil diets (highly saturated) contain about twice as much cholesteryl ester as those grown… 
Highly Cited
1976
Highly Cited
1976
Active-site-directed inactivation of aromatase from human placental microsomes by brominated androgen derivatives.
Several brominated androgen derivatives were tested for their ability to inactivate microsomal aromatase from term human placenta… 
Highly Cited
1971
Highly Cited
1971
Oxidation of cholesterol, 3 -hydroxy-5-pregnen-20-one and 3 -hydroxy-5-androsten-17-one by rat liver microsomes.
The metabolism of cholesterol, 3β-hydroxy-5-pregnen-20-one and 3β-hydroxy-5-androsten-17-one and the formation of lipid peroxides… 
Highly Cited
1969
Highly Cited
1969
Influence of steroid distribution between microsomes and soluble fraction on steroid metabolism by microsomal enzymes.
When progesterone labeled with one isotope and 17-hydroxyprogesterone labeled with another were incubated together in the… 
Highly Cited
1962
Highly Cited
1962
The lipid composition of rat-liver mitochondria, fluffy layer and microsomes.
The fatty acid compositions of the intracellular organelles of rat liver, separated by differential centrifuging, and the…