Microsomes, Liver

Known as: Liver Microsome, Liver Microsomes, Microsome, Liver 
Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
0204019512017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Hydroxylation of the antidepressant and smoking deterrent drug bupropion is a clinically important bioactivation and elimination… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table I
Is this relevant?
2006
2006
The utility of in vitro metabolism to accurately predict the clearance of hepatically metabolized drugs was evaluated. Three… (More)
  • table I
  • figure 1
  • table II
  • table III
  • table IV
Is this relevant?
2006
2006
Primary laboratory of origin: Division of Molecular Pharmaceutics, School of Pharmacy, The University of North Carolina at Chapel… (More)
  • table 1
  • table 2
Is this relevant?
2004
2004
Purpose. This study aims to evaluate a cytochrome P450-based tamoxifen-isoflavone interaction and to determine the mechanisms… (More)
  • figure 2
  • figure 1
  • figure 3
  • table I
  • figure 4
Is this relevant?
2002
2002
Purpose. To assess the contribution of drug metabolism to the variability on flavopiridol glucuronidation observed in cancer… (More)
  • figure 1
  • figure 2
  • table I
  • figure 3
  • table II
Is this relevant?
2000
2000
Purpose. To quantitatively predict the in vivo interaction betweentriazolam and erythromycin, which involves mechanism… (More)
  • figure 1
  • table 1
  • figure 3
  • figure 2
  • table 2
Is this relevant?
1999
1999
The biotransformation of venlafaxine (VF) into its two major metabolites, O-desmethylvenlafaxine (ODV) and N-desmethylvenlafaxine… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
1971
1971
Extract: Optimal conditions for the in vitro assay of bilirubin uridine diphospho- (UDP) glu-curonyltransferase activity in rat… (More)
  • table I
  • figure 1
  • figure 4
  • figure 7
  • figure 6
Is this relevant?
Highly Cited
1964
Highly Cited
1964
The presence in mammalian liver microsomes of a carbon monoxide-binding pigment has been reported by Klingenberg (1) and by… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table I
Is this relevant?
Highly Cited
1964