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Melatonin, the neurohormone of the pineal gland, is also produced by various other tissues and cells. It acts via G protein… Expand Melatonin is a ubiquitous molecule and widely distributed in nature, with functional activity occurring in unicellular organisms… Expand Melatonin is a methoxyindole synthesized and secreted principally by the pineal gland at night under normal environmental… Expand Abstract: Antioxidant enzymes form the first line of defense against free radicals in organisms. Their regulation depends mainly… Expand The photopigment in the human eye that transduces light for circadian and neuroendocrine regulation, is unknown. The aim of this… Expand Three centuries ago, the French philosopher Rene Descartes described the pineal gland as “the seat of the soul,” but it was not… Expand Foreword. Melatonin and the mammalian pineal gland. Structure of the pineal gland. Biochemistry of the pineal. Light-dark control… Expand We have compared the peroxyl radical scavenger ability to melatonin with that of vitamin E, vitamin C and reduced glutathione… Expand I. Introduction UNTIL 35 yr ago, most scientists did not take research on the pineal gland seriously. The decade beginning in… Expand Bright artificial light suppressed nocturnal secretion of melatonin in six normal human subjects. Room light of less intensity… Expand