2-iodomelatonin

Melatonin exerts its biological effects through at least two transmembrane G-protein-coupled receptors, MT1 and MT2, and a lower… (More)

Compelling evidence indicates that excessive K+ efflux and intracellular K+ depletion are key early steps in apoptosis… (More)

Activation of K(+) current plays a critical role in the control of programmed cell death. In the present study, whole-cell patch… (More)

Melatonin's O-methyl and N-acetyl residues are not only the basis of its amphilicity enabling the molecule to enter all organs… (More)

We have pharmacologically characterized recombinant human mt(1) and MT(2) receptors, stably expressed in Chinese hamster ovary… (More)

The neurohormone melatonin is a key agent in synchronizing the circadian rhythms. At least three types of binding sites have been… (More)

2[125I]Iodomelatonin binding sites were identified in the mucosa of the human colon from Chinese patients with carcinoma of the… (More)

Putative melatonin binding sites were detected in the membrane fraction of gonadotropin-stimulated human granulosa cells using… (More)

2-[125I]Iodomelatonin was found to bind specifically to the membrane preparations of the spleens of guinea pigs with high… (More)

2-[125I]Iodomelatonin binds with high affinity to a site possessing the pharmacological characteristics of a melatonin receptor… (More)