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2-iodomelatonin

Known as: Acetamide, N-(2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl)-, (3beta)-, N-(2-(2-iodo-5-methoxy-IH-indol-3-yl)ethyl)acetamide 
 
National Institutes of Health

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2 relations

Broader (1)

Melatonin
analogs & derivatives

Papers overview

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Highly Cited
2002
Highly Cited
2002
Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs.
Melatonin's O-methyl and N-acetyl residues are not only the basis of its amphilicity enabling the molecule to enter all organs… Expand
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Highly Cited
2002
Highly Cited
2002
Melatonin mt1 and MT2 receptors stimulate c-Jun N-terminal kinase via pertussis toxin-sensitive and -insensitive G proteins.
Melatonin is a pineal hormone involved in neuroendocrine processes in mammals. It has been shown that melatonin inhibits the… Expand
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Review
2000
Review
2000
Photic Regulation of mt1 Melatonin Receptors and 2-Iodomelatonin Binding in the Rat and Siberian Hamster
We have investigated the photic regulation of melatonin receptors both at the level of binding capacity and mt1 mRNA expression… Expand
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Highly Cited
2000
Highly Cited
2000
Pharmacological characterization of human recombinant melatonin mt(1) and MT(2) receptors.
We have pharmacologically characterized recombinant human mt(1) and MT(2) receptors, stably expressed in Chinese hamster ovary… Expand
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1999
1999
Characterization of 2-[125I]iodomelatonin binding sites in Syrian hamster peripheral organs.
The neurohormone melatonin is a key agent in synchronizing the circadian rhythms. At least three types of binding sites have been… Expand
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1996
1996
Melatonin and 2[125I]iodomelatonin binding sites in the human colon.
2[125I]Iodomelatonin binding sites were identified in the mucosa of the human colon from Chinese patients with carcinoma of the… Expand
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1993
1993
Autoradiographic localization of putative melatonin receptors in the brains of two Old World primates: Cercopithecus aethiops and Papio ursinus
The distribution of putative melatonin receptors in the brains of two Old World primates of the superfamily Catarrhina… Expand
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1992
1992
2[125I]iodomelatonin binding sites in spleens of guinea pigs.
2-[125I]Iodomelatonin was found to bind specifically to the membrane preparations of the spleens of guinea pigs with high… Expand
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Highly Cited
1990
Highly Cited
1990
Expression of melatonin receptors in arteries involved in thermoregulation.
Melatonin binding sites were localized and characterized in the vasculature of the rat by using the melatonin analogue 2-[125I… Expand
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Highly Cited
1987
Highly Cited
1987
Use of 2-[125I]iodomelatonin to characterize melatonin binding sites in chicken retina.
2-[125I]Iodomelatonin binds with high affinity to a site possessing the pharmacological characteristics of a melatonin receptor… Expand
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