Skip to search formSkip to main contentSkip to account menu

Lamivudine / Zidovudine

Known as: lamivudine, zidovudine drug combination, lamivudine zidovudine, lamivudine+zidovudine 
A combination of two synthetic nucleoside analogues with synergistic antiviral properties. Lamivudine is phosphorylated intracellularly to its active… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (4)

Anti-HIV AgentsDrug CombinationsReverse Transcriptase InhibitorsZidovudine

Narrower (1)

Combivir
Lamivudine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: the PENTA 5 randomised trial
Highly Cited
2002
Highly Cited
2002
Potency of Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) Used in Combination with Other Human Immunodeficiency Virus NNRTIs, NRTIs, or Protease Inhibitors
ABSTRACT Efavirenz and a series of related quinazolinone nonnucleoside inhibitors of the human immunodeficiency virus type 1 (HIV… 
Highly Cited
2001
Highly Cited
2001
Use of ESAT-6 and CFP-10 antigens for diagnosis of extrapulmonary tuberculosis.
1. Doukhan L, Delwart EL. Use of tissue culture–amplified human immunodeficiency virus type 1 to study evolutionary changes in… 
Highly Cited
2001
Highly Cited
2001
Genotypic and Phenotypic Resistance Patterns of Human Immunodeficiency Virus Type 1 Variants with Insertions or Deletions in the Reverse Transcriptase (RT): Multicenter Study of Patients Treated with…
ABSTRACT Genomic rearrangements in the 5′ part of the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) have… 
Highly Cited
2000
Highly Cited
2000
Simultaneous determination of lamivudine and zidovudine concentrations in human seminal plasma using high-performance liquid chromatography and tandem mass spectrometry.
Highly Cited
2000
Highly Cited
2000
Evidence of a Role for the Q151L Mutation and the Viral Background in Development of Multiple Dideoxynucleoside-Resistant Human Immunodeficiency Virus Type 1
ABSTRACT The majority of human immunodeficiency virus type 1 (HIV-1)-infected patients treated with zidovudine (AZT) plus… 
Highly Cited
1999
Highly Cited
1999
Thalidomide stimulates T cell responses and interleukin 12 production in HIV-infected patients.
We performed a placebo-controlled study to evaluate the effects of immunomodulatory treatment with thalidomide on HIV levels, TNF… 
Review
1999
Review
1999
Treatment with amprenavir alone or amprenavir with zidovudine and lamivudine in adults with human immunodeficiency virus infection. AIDS Clinical Trials Group 347 Study Team.
Amprenavir is a human immunodeficiency virus (HIV) protease inhibitor with a favorable pharmacokinetic profile and good in vitro… 
Highly Cited
1998
Highly Cited
1998
A dose‐ranging study to evaluate the safety and efficacy of abacavir alone or in combination with zidovudine and lamivudine in antiretroviral treatment‐naive subjects
Objective:To compare antiretroviral efficacy, safety and tolerance of three dosing regimens of the novel nucleoside reverse… 
Highly Cited
1996
Highly Cited
1996
Zidovudine resistance is suppressed by mutations conferring resistance of human immunodeficiency virus type 1 to foscarnet
Both foscarnet (PFA) and zidovudine (AZT) select for drug-resistant variants of human immunodeficiency virus type 1 (HIV-1), but… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)