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Lamivudine

Known as: 3TC, 2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-, 2',3'-Dideoxy-3'-thiacytidine 
A synthetic nucleoside analogue with activity against hepatitis B virus (HBV) and HIV. Intracellularly, lamivudine is phosphorylated to its active… 
National Institutes of Health

Related topics

Related topics

33 relations

Broader (3)

Anti-HIV AgentsHividZalcitabine

Narrower (9)

CombivirEpivirEpzicomGR-109714X
Hepatitis BIn BloodLamivudine / Nevirapine / StavudineLamivudine 100 MG Oral Tablet [Epivir HBV]

Papers overview

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2007
2007
Nonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L- and D-nucleosides.
Biological molecules are predominantly enantioselective. Yet currently two nucleoside analogue prodrugs (3TC and FTC) with… 
Highly Cited
2001
Highly Cited
2001
Microsatellite analysis of genetic diversity in sweetpotato varieties from Latin America.
Sweetpotato (Ipomoea batatas (L.) Lam.) was originally domesticated in tropical America. The sweetpotato gene bank maintained at… 
Review
1998
Review
1998
Investigation of a New Family of Chiral Ligands for Enantioselective Catalysis via Parallel Synthesis and High‐Throughput Screening.
Applications of combinatorial chemistry are widespread and cover fields as diverse as drug discovery and optimization,1 material… 
Review
1998
Review
1998
Mycobacterial lipids: a historical perspective.
Mycobacterial lipids have been studied for more than 70 years, due to the fascinating diversity of their structures and… 
Highly Cited
1981
Highly Cited
1981
Inhibition in vivo of the formation of adducts between metabolites of benzo(a)pyrene and DNA by butylated hydroxyanisole.
Antioxidants have been shown to inhibit the carcinogenic effects of a variety of chemical carcinogens. For example, the phenolic… 
Highly Cited
1978
Highly Cited
1978
A fungitoxic principle from the leaves ofLawsonia inermis Lam.
During antifungal screening of higher plants, the leaves ofLawsonia inermis were found to exhibit strong fungitoxicity. On… 
Highly Cited
1973
Highly Cited
1973
Herpes simplex and zoster.
4 Barltrop, D., and Burland, W. C., Mineral Metabolism in Paediatrics, p. 135. Oxford, Bladkwell Scientific, 1969. ' Robinson, M… 
Highly Cited
1968
Highly Cited
1968
Nodulation of Tropical Legumes I. Specificity in the Rhizobium Symbiosis of Leucaena leucocephala
Summary Leucaena leucocephala (Lam.) de Wit. failed to nodulate with 94 of the 99 strains of Rhizobium tested, representing the… 
1968
1968
Antifertility screening of plants: 1. Investigations on Butea monosperma (Lam.) Kuntze.
Butea monosperma belonging to the family of leguminosae grows abundantly in India. It has been reported to possess an… 
Highly Cited
1964
Highly Cited
1964
Freezing Processes in the Crown of ‘Hudson’ Barley, Hordeum vulgare (L., emend. Lam.) Hudson 1
U normal conditions for growth, water is distributed between the space inside and outside of the living protoplasts in a balanced…