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Lamivudine

Known as: 3TC, 2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-, 2',3'-Dideoxy-3'-thiacytidine 
A synthetic nucleoside analogue with activity against hepatitis B virus (HBV) and HIV. Intracellularly, lamivudine is phosphorylated to its active… 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
5. Tools available and ways to submit data to PX ............................................................. 11 5.1. MS/MS data… 
Highly Cited
2006
Highly Cited
2006
BACKGROUND Entecavir is a potent and selective guanosine analogue with significant activity against hepatitis B virus (HBV… 
Highly Cited
2006
Highly Cited
2006
BACKGROUND Entecavir is a potent and selective antiviral agent that has demonstrated efficacy in phase 2 studies in patients with… 
Highly Cited
2005
Highly Cited
2005
BACKGROUND Current treatments for chronic hepatitis B are suboptimal. In the search for improved therapies, we compared the… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND The effectiveness of antiviral therapy in preventing disease progression in patients with chronic hepatitis B and… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND Available treatments for hepatitis B e antigen (HBeAg)-negative chronic hepatitis B are associated with poor sustained… 
Highly Cited
2003
Highly Cited
2003
BACKGROUND & AIMS One year of lamivudine for chronic hepatitis B results in histologic improvement. We aimed to assess the… 
Highly Cited
1999
Highly Cited
1999
BACKGROUND AND METHODS Although the nucleoside analogue lamivudine has shown promise in patients with chronic hepatitis B, long… 
Highly Cited
1998
Highly Cited
1998
BACKGROUND AND METHODS In preliminary trials, lamivudine, an oral nucleoside analogue, has shown promise for the treatment of… 
Highly Cited
1997
Highly Cited
1997
BACKGROUND The new protease inhibitors are potent inhibitors of the human immunodeficiency virus (HIV), and in combination with…