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Zalcitabine

Known as: Cytidine, 2',3'-dideoxy-, Zalcitabine [Chemical/Ingredient], DDC 
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the… 
National Institutes of Health

Related topics

Related topics

23 relations

Broader (4)

2',3'-DideoxynucleosidesAnti-HIV AgentsAntimetabolitesReverse Transcriptase Inhibitors

Narrower (8)

2',3'-dideoxycytidine monophosphate diglyceride2',3'-dideoxycytidineneBCH-189Epivir
Acquired Immunodeficiency SyndromeDrug AllergyIn BloodNCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells
Recent studies have challenged the view that Langerhans cells (LCs) constitute the exclusive antigen-presenting cells of the skin… 
Highly Cited
2003
Highly Cited
2003
Mouse A6–positive hepatic oval cells also express several hematopoietic stem cell markers
Hepatic oval cells (HOC) are thought to be a type of facultative stem cell that arises as a result of certain forms of hepatic… 
Highly Cited
1999
Highly Cited
1999
Inhibition of copper-zinc superoxide dismutase induces cell growth, hypertrophic phenotype, and apoptosis in neonatal rat cardiac myocytes in vitro.
Oxidative stress has been implicated in the pathophysiology of myocardial failure. We tested the hypothesis that inhibition of… 
Highly Cited
1997
Highly Cited
1997
Line probe assay for rapid detection of drug-selected mutations in the human immunodeficiency virus type 1 reverse transcriptase gene
Upon prolonged treatment with various antiretroviral nucleoside analogs such as 3'-azido-3'-deoxythymidine, 2',3'-dideoxyinosine… 
Highly Cited
1997
Highly Cited
1997
Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus
The template for synthesis of hepadnaviral RNAs is a covalently closed circular (ccc) DNA located in the nucleus of the infected… 
Highly Cited
1994
Highly Cited
1994
Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450.
A variety of chemicals, including triacetyloleandomycin (TAO), alpha-naphthoflavone (ANF), and diethyldithiocarbamate (DDC), are… 
Highly Cited
1994
Highly Cited
1994
Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein.
Expression screening in Xenopus oocytes was used to isolate a cDNA from rat jejunal epithelium encoding a Na(+)-dependent… 
Highly Cited
1993
Highly Cited
1993
The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3…
Variants of human immunodeficiency virus type 1 that display 500- to 1,000-fold resistance to the (-) enantiomer of 2'-deoxy-3… 
Highly Cited
1992
Highly Cited
1992
Generation of reactive oxygen metabolites by the haemocytes of the mussel Mytilus edulis.
Highly Cited
1992
Highly Cited
1992
Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine
We have used the technique of in vitro selection to generate variants of human immunodeficiency virus type 1 (HIV-1) that are… 
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