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Zalcitabine

Known as: Cytidine, 2',3'-dideoxy-, Zalcitabine [Chemical/Ingredient], DDC 
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the… 
National Institutes of Health

Related topics

Related topics

23 relations

Broader (4)

2',3'-DideoxynucleosidesAnti-HIV AgentsAntimetabolitesReverse Transcriptase Inhibitors

Narrower (8)

2',3'-dideoxycytidine monophosphate diglyceride2',3'-dideoxycytidineneBCH-189Epivir
Acquired Immunodeficiency SyndromeDrug AllergyIn BloodNCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Involvement of the hippocampal CA3-region in acquisition and in memory consolidation of spatial but not in object information in mice
Highly Cited
2002
Highly Cited
2002
Phosphorylation of Pyrimidine Deoxynucleoside Analog Diphosphates
d-Nucleoside analogs, which are in the natural configuration, as well as the l-nucleoside analogs, are clinically relevant… 
Highly Cited
1992
Highly Cited
1992
Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication.
Highly Cited
1989
Highly Cited
1989
Molecular cloning and sequencing of a cDNA of rat dopa decarboxylase: partial amino acid homologies with other enzymes synthesizing catecholamines.
Dopa decarboxylase (DDC; aromatic-L-amino-acid decarboxylase; aromatic-L-amino-acid carboxylase, EC 4.1.1.28) was purified from… 
Highly Cited
1987
Highly Cited
1987
Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3…
We report that 2',3'-dideoxyadenosine and 2',3'-dideoxycytidine inhibit retroviral DNA synthesis and mRNA expression in T cells… 
Highly Cited
1987
Highly Cited
1987
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
Various 3'-azido, 3'-amino, 2',3'-unsaturated, 2',3'-dideoxy, and 5-substituted analogues of pyrimidine deoxyribonucleosides have… 
Highly Cited
1987
Highly Cited
1987
Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogues.
5-Substituted 2',3'-dideoxycytidine analogues have been synthesized and evaluated in vitro for their capabilities to protect T4… 
Highly Cited
1986
Highly Cited
1986
Potent and selective anti-HTLV-III/LAV activity of 2',3'-dideoxycytidinene, the 2',3'-unsaturated derivative of 2',3'-dideoxycytidine.
Highly Cited
1977
Highly Cited
1977
Evidence for interactions between central noradrenergic neurons and adrenal hormones in learning and memory
Highly Cited
1975
Highly Cited
1975
Biphasic induction of ornithine decarboxylase and putrescine levels in growing HTC cells.
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