Skip to search formSkip to main contentSkip to account menu

Reverse Transcriptase Inhibitors

Known as: Inhibitors, Reverse Transcriptase, Viral Reverse Transcriptase Inhibitor, Reverse Transcriptase Inhibitor 
Any substance that inhibits the activity of viral reverse transcriptase, an RNA-dependent DNA polymerase that transcribes viral RNA into DNA during… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (35)

2',3'-DideoxynucleosidesDelavirdineDidanosineDideoxynucleosides

Broader (3)

Anti-HIV AgentsAntiviral AgentsEnzyme Inhibitors
HIVIn Bloodaspects of radiation effectschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Simultaneous HPLC Determination of Efavirenz, 8-hydroxy Efavirenz, Neostigmine and Comparison of their Separation Using a C18 and Biphenyl Column through Pharmacological Evaluation
A simple, rapid and stable high performance liquid chromatography method for a combination of efavirenz, its major metabolite 8… 
2013
2013
Arylazolylthioacetanilide. Part 11: design, synthesis and biological evaluation of 1,2,4-triazole thioacetanilide derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
A series of novel 1,2,4-triazole thioacetanilide derivatives has been designed, synthesized and evaluated for their anti-HIV… 
2005
2005
Structure based activity prediction of HIV-1 reverse transcriptase inhibitors.
We have developed a fast and robust computational method for prediction of antiviral activity in automated de novo design of HIV… 
2004
2004
Virological and immunological impact of non-nucleoside reverse transcriptase inhibitor withdrawal in HIV-infected patients with multiple treatment failures
No significant changes in viral load and CD4 cell count were observed 2-4 weeks after the withdrawal of non-nucleoside reverse… 
2003
2003
Comparison of metabolic abnormalities 48 weeks after switching from highly active antiretroviral therapy containing a non-nucleoside reverse transcriptase inhibitor to Trizivir versus continued…
Forty patients participating in the TRIZAL study were treated with a non-nucleoside reverse transcriptase inhibitor (NNRTI… 
2002
2002
Anti-HIV reverse transcriptase inhibitor
Infection with HIV-1 remains a global health problem and due to the emergence of drug-resistant HIV variants, there is an ongoing… 
2002
2002
Dietary supplements in the treatment of nucleoside reverse transcriptase inhibitor-related mitochondrial toxicity.
2001
2001
Pharmacokinetics and safety of escalating single and repeat oral doses of GW420867X, a novel non-nucleoside reverse transcriptase inhibitor
Abstract Objective: To assess the pharmacokinetics, safety and tolerability of escalating oral doses of GW420867X, a non… 
1999
1999
Calanolide A: a natural non-nucleoside reverse transcriptase inhibitor.
Calanolide A, an experimental non-nucleoside reverse transcriptase inhibitor, is a synthetic version of a compound found in… 
1995
1995
New non-nucleoside reverse transcriptase inhibitor.
A new class of drugs called non-nucleoside reverse transcriptase inhibitors are entering phase I clinical trials according to…