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Reverse Transcriptase Inhibitors

Known as: Inhibitors, Reverse Transcriptase, Viral Reverse Transcriptase Inhibitor, Reverse Transcriptase Inhibitor 
Any substance that inhibits the activity of viral reverse transcriptase, an RNA-dependent DNA polymerase that transcribes viral RNA into DNA during… 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
We previously proposed that a balance between nucleotide excision and template RNA degradation plays an important role in… 
Highly Cited
2007
Highly Cited
2007
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of human… 
Highly Cited
2006
Highly Cited
2006
OBJECTIVE To determine the incidence of and predisposing risk factors for lactic acidosis in HIV-infected patients on… 
Highly Cited
2002
Highly Cited
2002
ABSTRACT Removal of nucleoside chain terminator inhibitors mediated by human immunodeficiency virus (HIV) reverse transcriptase… 
Highly Cited
2002
Highly Cited
2002
ABSTRACT Efavirenz and a series of related quinazolinone nonnucleoside inhibitors of the human immunodeficiency virus type 1 (HIV… 
Highly Cited
2001
Highly Cited
2001
BackgroundEnhanced susceptibility to non-nucleoside reverse transcriptase inhibitors (NNRTI) was recently described in… 
Highly Cited
1998
Highly Cited
1998
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) strains resistant to nonnucleoside reverse transcriptase inhibitors (NNRTIs… 
Highly Cited
1995
Highly Cited
1995
4-(Arylthio)-pyridin-2(1H)-ones variously substituted in their 3-, 5-, and 6-positions have been synthesized as a new series of 1… 
Highly Cited
1995
Highly Cited
1995
HBY 097 [(S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthiomethyl)-3, 4-dihydroquinoxaline-2(1H)-thione] was selected from a series…