Skip to search formSkip to main contentSkip to account menu

Reverse Transcriptase Inhibitors

Known as: Inhibitors, Reverse Transcriptase, Viral Reverse Transcriptase Inhibitor, Reverse Transcriptase Inhibitor 
Any substance that inhibits the activity of viral reverse transcriptase, an RNA-dependent DNA polymerase that transcribes viral RNA into DNA during… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (35)

2',3'-DideoxynucleosidesDelavirdineDidanosineDideoxynucleosides

Broader (3)

Anti-HIV AgentsAntiviral AgentsEnzyme Inhibitors
HIVIn Bloodaspects of radiation effectschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
HIV-1 Reverse Transcriptase Plus-strand Initiation Exhibits Preferential Sensitivity to Non-nucleoside Reverse Transcriptase Inhibitors in Vitro*
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of human… 
2007
2007
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors
A structure-based molecular modeling approach was performed to identify novel structural characteristics and scaffolds that might… 
Highly Cited
2005
Highly Cited
2005
Determination of antiretroviral agents in human serum by capillary electrophoresis.
Review
2003
Review
2003
Long-term complications of nucleoside reverse transcriptase inhibitor therapy.
HAART has resulted in dramatic declines in morbidity and mortality among patients infected with HIV. Increased experience with… 
Review
1999
Review
1999
Transport, metabolism and elimination mechanisms of anti-HIV agents.
Highly Cited
1998
Highly Cited
1998
Patterns of Resistance and Cross-Resistance to Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors in Patients Treated with the Nonnucleoside Reverse Transcriptase Inhibitor Loviride
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) strains resistant to nonnucleoside reverse transcriptase inhibitors (NNRTIs… 
Highly Cited
1995
Highly Cited
1995
Preclinical evaluation of HBY 097, a new nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 replication
HBY 097 [(S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthiomethyl)-3, 4-dihydroquinoxaline-2(1H)-thione] was selected from a series… 
1994
1994
HIV-1 reverse transcriptase inhibitor design using artificial neural networks.
Artificial neural networks were used to analyze and predict the human immunodeficiency virus type 1 reverse transcriptase… 
Highly Cited
1994
Highly Cited
1994
Susceptibilities of human immunodeficiency virus type 1 enzyme and viral variants expressing multiple resistance-engendering amino acid substitutions to reserve transcriptase inhibitors
To evaluate the potential that multiply resistant human immunodeficiency virus type 1 variants may arise during combination… 
1990
1990
A New stereospecific synthesis of [3.1.0]bicyclic cyclopropano analog of 2'3'-dideoxyuridine
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)