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Reverse Transcriptase Inhibitors

Known as: Inhibitors, Reverse Transcriptase, Viral Reverse Transcriptase Inhibitor, Reverse Transcriptase Inhibitor 
Any substance that inhibits the activity of viral reverse transcriptase, an RNA-dependent DNA polymerase that transcribes viral RNA into DNA during… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND The non-nucleoside reverse transcriptase inhibitor (NNRTI), rilpivirine (TMC278; Tibotec Pharmaceuticals, County Cork… Expand
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Review
2010
Review
2010
Twenty-five years ago, nucleoside analog 3'-azidothymidine (AZT) was shown to efficiently block the replication of HIV in cell… Expand
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Highly Cited
2004
Highly Cited
2004
Anti-AIDS drug candidate and non-nucleoside reverse transcriptase inhibitor (NNRTI) TMC125-R165335 (etravirine) caused an initial… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are potent inhibitors of human immunodeficiency virus type 1… Expand
Review
2001
Review
2001
BACKGROUND Hypersensitivity reactions consist of a variable group of clinical findings and have been described for a wide variety… Expand
Review
2000
Review
2000
  • T. Kakuda
  • Clinical therapeutics
  • 2000
  • Corpus ID: 32975431
OBJECTIVE This paper reviews the function of the mitochondria and the mechanisms by which nucleoside and nucleotide reverse… Expand
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Highly Cited
2000
Highly Cited
2000
BackgroundProgressive subcutaneous fat wasting, fat accumulation, dyslipidaemia and insulin resistance in HIV-infected patients… Expand
Highly Cited
2000
Highly Cited
2000
Through computationally directed broad screening, a novel 1, 5-diphenylpyrazole (DPP) class of HIV-1 nonnucleoside reverse… Expand
Highly Cited
1993
Highly Cited
1993
Resistant variants of human immunodeficiency virus type 1 (HIV-1) have been selected by limited passage in MT4 cells of both wild… Expand
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Highly Cited
1990
Highly Cited
1990
A series of dipyridodiazepinones have been shown to be potent inhibitors of human immunodeficiency virus-1 (HIV-1) reverse… Expand