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Delavirdine

Known as: Delavirdin, 1-(3-((1-Methylethyl)amino)-2-pyridinyl)-4-((5-((methylsulfonyl)amino)-1H-indol-2-yl)carbonyl)piperazine, Delavirdina 
A synthetic, non-nucleoside reverse transcriptase inhibitor. In combination with other anti-retroviral drugs, this agent has been shown to reduce HIV… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
In 2008, 25 years after the human immunodeficiency virus (HIV) was discovered as the then tentative aetiological agent of… Expand
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Review
2008
Review
2008
Human cytochrome P450 (CYP) 3A4 is the most abundant hepatic and intestinal phase I enzyme that metabolizes approximately 50… Expand
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Highly Cited
2007
Highly Cited
2007
Permeability of the anti-human immunodeficiency virus (HIV) agents, including stavudine (D4T), delavirdine (DLV), and saquinavir… Expand
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2005
2005
Methamphetamine causes persistent damage to dopamine nerve endings of the striatum. The mechanisms underlying its neurotoxicity… Expand
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Highly Cited
2004
Highly Cited
2004
Limited information is available on the activity of antiretroviral drugs against human immunodeficiency virus type 2 (HIV-2) and… Expand
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Highly Cited
2003
Highly Cited
2003
Some small molecules, often hits from screening, form aggregates in solution that inhibit many enzymes. In contrast, drugs are… Expand
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Highly Cited
2001
Highly Cited
2001
Efavirenz (also known as DMP 266 or SUSTIVA) is a potent nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1… Expand
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Highly Cited
2000
Highly Cited
2000
Through computationally directed broad screening, a novel 1, 5-diphenylpyrazole (DPP) class of HIV-1 nonnucleoside reverse… Expand
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Review
1999
Review
1999
There are 3 groups of drugs available for the treatment of patients with HIV disease. These are the nucleoside reverse… Expand
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Highly Cited
1993
Highly Cited
1993
1. NS-398 (N-[2-cyclohexyloxy-4-nitrophenyl] methanesulfonamide) is a new non-steroidal anti-inflammatory drug (NSAID) with… Expand
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