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Alprazolam

Known as: 4H-(1,2,4)Triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-1-methyl-6-phenyl-, Alprazolan, Alprazolam [Chemical/Ingredient] 
A triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities. Alprazolam binds to a specific site distinct from… 
National Institutes of Health

Related topics

Related topics

33 relations
24 HR Alprazolam 1 MG Extended Release Oral TabletAgoraphobiaAlprazolam 0.25 MG Oral TabletAlprazolam 1 MG Disintegrating Oral Tablet

Narrower (10)

4-hydroxyalprazolamAlproxCassadanD-65MT

Broader (5)

Anti-Anxiety AgentsBenzodiazepineGABA ModulatorsHypnotics and Sedatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Environmental impact of pharmaceuticals from Portuguese wastewaters: geographical and seasonal occurrence, removal and risk assessment.
Review
2012
Review
2012
Interactions Between Herbal Medicines and Prescribed Drugs
The concomitant use of herbal medicines and pharmacotherapy is wide spread. We have reviewed the literature to determine the… 
Highly Cited
2011
Highly Cited
2011
Overexpression of CB2 cannabinoid receptors decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice
Mice overexpressing CB2r (CB2xP) were exposed to open field (OF), light–dark box (LDB) and elevated plus maze (EPM) tests… 
Highly Cited
2007
Highly Cited
2007
Seizure Incidence in Psychopharmacological Clinical Trials: An Analysis of Food and Drug Administration (FDA) Summary Basis of Approval Reports
Review
2006
Review
2006
Clinical pharmacology, clinical efficacy, and behavioral toxicity of alprazolam: a review of the literature.
Alprazolam is a benzodiazepine derivative that is currently used in the treatment of generalized anxiety, panic attacks with or… 
Highly Cited
2005
Highly Cited
2005
Pregabalin for treatment of generalized anxiety disorder: a 4-week, multicenter, double-blind, placebo-controlled trial of pregabalin and alprazolam.
BACKGROUND Pregabalin inhibits release of excess excitatory neurotransmitters, presumably by binding to the alpha2-delta subunit… 
Review
1998
Review
1998
In vitro approaches to predicting drug interactions in vivo.
Highly Cited
1995
Highly Cited
1995
Dorsal periaqueductal gray-induced aversion as a simulation of panic anxiety: Elements of face and predictive validity
Review
1993
Review
1993
Clinical Pharmacokinetics of Alprazolam
SummaryAlprazolam is a triazolobenzodiazepine that is extensively prescribed in the Western world for the treatment of anxiety… 
Highly Cited
1988
Highly Cited
1988
Alprazolam in panic disorder and agoraphobia: results from a multicenter trial. III. Discontinuation effects.
Preliminary reports of discontinuation of alprazolam therapy in patients with panic disorder have revealed worsening of symptoms… 
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