Skip to search formSkip to main contentSkip to account menu

Zidovudine

Known as: 3'-Azido-2',3'-Dideoxythymidine, Azidothymidine, Antiviral AZT 
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
We previously proposed that a balance between nucleotide excision and template RNA degradation plays an important role in… 
Highly Cited
2002
Highly Cited
2002
Mitochondrial functional and structural impairment and generation of oxidative stress have been implicated in aging, various… 
Highly Cited
2000
Highly Cited
2000
3'-azido-3'-deoxythymidine (AZT) is given to pregnant women positive for the human immunodeficiency virus type 1 (HIV-1) to… 
Highly Cited
1999
Highly Cited
1998
Highly Cited
1998
AbstractPurpose. This study characterized the cellular uptake mechanism and hydrolysis of the amino acid ester prodrugs of… 
Highly Cited
1993
Highly Cited
1993
Identifying a valid surrogate end point for serious clinical events associated with human immunodeficiency virus (HIV) infection… 
Highly Cited
1989
Highly Cited
1989
The triphenylmethane derivative aurintricarboxylic acid (ATA), but not aurin, selectively prevented the binding of OKT4A/Leu-3a… 
Highly Cited
1988
Highly Cited
1988
Peripheral blood cytopenias are a serious, dose‐limiting toxicity of AZT therapy in patients infected by HIV. To evaluate the… 
Highly Cited
1988
Highly Cited
1988
We evaluated the effects of natural purine and pyrimidine nucleosides on protection from or reversal of 3'-azido-3…