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Zidovudine

Known as: 3'-Azido-2',3'-Dideoxythymidine, Azidothymidine, Antiviral AZT 
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
ABSTRACT 2017 marked the 30th anniversary of the approval of zidovudine (AZT) as the first HIV/AIDS therapy. Since then, more… Expand
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Review
2018
Review
2018
The ProTide technology is a prodrug approach developed for the efficient intracellular delivery of nucleoside analogue… Expand
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Review
2018
Review
2018
Viral RNA-dependent RNA polymerases (RdRps) play a central role not only in viral replication, but also in the genetic evolution… Expand
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Highly Cited
2010
Highly Cited
2010
In the domain of health, one important challenge is the efficient delivery of drugs in the body using non-toxic nanocarriers… Expand
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Highly Cited
2000
Highly Cited
2000
Standard methods for survival analysis, such as the time-dependent Cox model, may produce biased effect estimates when there… Expand
Highly Cited
1999
Highly Cited
1999
BACKGROUND Many developing countries have not implemented the AIDS Clinical Trials Group 076 zidovudine regimen for prevention of… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The new protease inhibitors are potent inhibitors of the human immunodeficiency virus (HIV), and in combination with… Expand
Highly Cited
1994
Highly Cited
1994
BACKGROUND AND METHODS Maternal-infant transmission is the primary means by which young children become infected with human… Expand
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Highly Cited
1989
Highly Cited
1989
The drug sensitivities of human immunodeficiency virus (HIV) isolates from a group of patients with acquired immunodeficiency… Expand
Highly Cited
1987
Highly Cited
1987
We conducted a double-blind, placebo-controlled trial of the efficacy of oral azidothymidine (AZT) in 282 patients with the… Expand