FAQ

Thymidine

Known as: dT, Thymidin, TDR 
A pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs… (More)

Topic mentions per year

Topic mentions per year

1947-2018
05001000150019472017

Related topics

Related topics

50 relations

Narrower (42)

2',3'-anhydrothymidine2'-Deoxythymidine2'-chlorothymidine2'-deoxythymidine-5'-monophosphate
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Broader (2)

DeoxyribonucleosidesPyrimidine Nucleosides
Process of secretionThymidine Kinaseadministration & dosageantagonists & inhibitors
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Related mentions per year

Related mentions per year

1938-2018
19401960198020002020
Thymidine
Zidovudine
Thymidine Kinase
chemical synthesis
Deoxyribonucleosides
Pyrimidine Nucleosides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Validation of FLT uptake as a measure of thymidine kinase-1 activity in A549 carcinoma cells.
UNLABELLED The thymidine analog (18)F-3'-deoxy-3' -fluorothymidine (FLT) is being used clinically for PET imaging of tumor… (More)
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Highly Cited
2001
Highly Cited
2001
Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy
The mitochondrial deoxyribonucleotide (dNTP) pool is separated from the cytosolic pool because the mitochondria inner membrane is… (More)
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Highly Cited
2000
Highly Cited
2000
Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus.
Recent studies suggest that stress-induced atrophy and loss of hippocampal neurons may contribute to the pathophysiology of… (More)
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Highly Cited
2000
Highly Cited
2000
Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.
We had previously shown that high gene expressions (mRNA levels) of thymidylate synthase (TS; Leichman et al., J. Clin. Oncol… (More)
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Highly Cited
1999
Highly Cited
1999
Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder.
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive human disease associated with multiple… (More)
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Highly Cited
1999
Highly Cited
1999
Learning enhances adult neurogenesis in the hippocampal formation
Thousands of hippocampal neurons are born in adulthood, suggesting that new cells could be important for hippocampal function. To… (More)
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Highly Cited
1998
Highly Cited
1998
Neurogenesis in the adult human hippocampus
The genesis of new cells, including neurons, in the adult human brain has not yet been demonstrated. This study was undertaken to… (More)
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Highly Cited
1986
Highly Cited
1986
Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy.
The lack of highly exploitable biochemical differences between normal tissues and some tumors can theoretically be circumvented… (More)
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Highly Cited
1980
Highly Cited
1980
Development of the hippocampal region in the rat. I. Neurogenesis examined with 3H-thymidine autoradiography.
Neurogenesis in the rat hippocampal region was examined with 3R-thymidine autoradiography. The rats in the prenatal groups were… (More)
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Highly Cited
1965
Highly Cited
1965
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats.
In the autoradiograms of young rats injected with thymidine-H3 many of the granule cells of the dentate gyrus were found labeled… (More)
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