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Thymidine Kinase

Known as: EC 2.7.1.21, Kinase, Deoxypyrimidine, Kinase, Thymidine 
An enzyme that catalyzes the conversion of ATP and thymidine to ADP and thymidine 5'-phosphate. Deoxyuridine can also act as an acceptor and dGTP as… 
National Institutes of Health

Related topics

Related topics

20 relations
Enzyme GeneIn BloodPhosphorylationPhosphotransferases

Broader (1)

Phosphotransferases, ATP

Narrower (5)

TK1 protein, humanTK2 protein, humanexposed proliferation antigen 210herpes simplex thymidine kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1990
Highly Cited
1990
Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells.
The mouse lymphoma L5178Y TK+/- 3.7.2C cell line allows quantitation of induced TK(+/-)----TK-/- mutations at the heterozygous… 
Highly Cited
1980
Highly Cited
1980
Expression of the herpes thymidine kinase gene in Xenopus laevis oocytes: an assay for the study of deletion mutants constructed in vitro.
When Xenopus laevis oocyte nuclei are injected with a recombinant plasmid containing the Herpes Simplex Virus (HSV) thymidine… 
Highly Cited
1980
Highly Cited
1980
Parameters governing the transfer of the genes for thymidine kinase and dihydrofolate reductase into mouse cells using metaphase chromosomes or DNA
The conditions necessary to achieve high frequency transfer of the thymidine kinase and dihydrofolate reductase genes from… 
Highly Cited
1979
Highly Cited
1979
Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1.
The gene for the thymidine kinase (TK) of Herpes simplex virus type 1 (HSV-1) is located in the KpnI m and BamHI p fragments of… 
Highly Cited
1977
Highly Cited
1977
Biochemical transformation of mouse cells by fragments of herpes simplex virus DNA
Highly Cited
1976
Highly Cited
1976
Deoxythymidine kinase induced in HeLa TK- cells by herpes simplex virus type I and type II. II. Purification and characterization.
Highly Cited
1974
Highly Cited
1974
Biochemical studies on the herpes simplex virus-specified deoxypyrimidine kinase activity.
Summary The response to various stimuli of herpes simplex virus-specified deoxypyrimidine kinase activity differs significantly… 
Highly Cited
1965
Highly Cited
1965
Properties of deoxythymidine kinase partially purified from animal tumors.
Highly Cited
1965
Highly Cited
1965
Studies on "early" enzymes in HeLa cells infected with vaccinia virus.
Highly Cited
1964
Highly Cited
1964
DEOXYTHYMIDINE KINASE OF ESCHERICHIA COLI. II. KINETICS AND FEEDBACK CONTROL.
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