TK1 protein, human

Known as: EC 2.7.1.21, TK1, thymidine kinase 1, soluble protein, human 
Thymidine kinase, cytosolic (234 aa, ~25 kDa) is encoded by the human TK1 gene. This protein plays a role in pyrimidine metabolism.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Thymidine kinase (TK1) is a key enzyme in the salvage pathway of deoxyribonucleotide metabolism, catalyzing the first step in the… (More)
Is this relevant?
2008
2008
The site-specific conjugation of metal chelating systems to biologically relevant molecules is an important contemporary topic in… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
Is this relevant?
2004
2004
Thymidine analogs containing o-carboranylalkyl groups at the 3-position were screened as potential substrates for human thymidine… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
2004
2004
Two analogs of the natural nucleoside dT featuring a pseudosugar with fixed conformation in place of the deoxyribosyl residue… (More)
Is this relevant?
2002
2002
To explore the expression of cytosolic thymidine kinase 1 (TK1) as a cell proliferative marker in human breast cancers… (More)
Is this relevant?
2000
2000
BACKGROUND Proliferation markers are necessary for reliable diagnosis. Here we have presented for the first time thymidine kinase… (More)
Is this relevant?
1998
1998
2'-Fluoro-5-methyl-beta-L-arabinofuranosyluracil (L-FMAU) is the first L-nucleoside analog with low cytotoxicity discovered to… (More)
Is this relevant?
1995
1995
Thymidine kinase (TK) is involved in DNA synthesis by the salvage pathway. In this study, thymidine kinase (TK) was determined in… (More)
Is this relevant?
1992
1992
Recent evidence suggests that the human neuromuscular disorders, hyperkalemic periodic paralysis and paramyotonia congenita, are… (More)
  • figure 1
  • table 1
Is this relevant?
1982
1982
Human thymidine kinase TK1 isoenzyme has been purified 1 800-fold from placenta to a specific activity of 2.9 nmoles/min/mg of… (More)
  • table 1
  • table 2
  • table 3
Is this relevant?