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Thymidine Phosphorylase

Known as: EC 2.4.2.4, Platelet-Derived Endothelial Cell Growth Factor 1, Platelet Derived Endothelial Cell Growth Factor 
Thymidine phosphorylase (482 aa, ~50 kDa) is encoded by the human TYMP gene. This protein plays a role in pyrimidine metabolism, DNA replication and… 
National Institutes of Health

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Related topics

25 relations
Angiogenic ProcessCarbohydrate MetabolismEnzyme GeneGlial Cell Proliferation

Broader (1)

pentosyltransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Дифференциальная диагностика митохондриальной нейрогастроинтестинальной энцефаломиопатии. Первое клиническое описание в России
Mitochondrial neurogastrointestinal encephalomyopathy syndrome (MNGIE) is a rare autosomal recessive progressive multisystem… 
2012
2012
099 Erythrocyte entrapped thymidine phosphorylase (EE-TP) therapy for mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)
MNGIE is a fatal, autosomal recessive disorder caused by mutations in TYMP, a nuclear gene encoding thymidine phosphorylase (TP… 
2010
2010
Emergency surgery in chronic intestinal pseudo-obstruction due to mitochondrial neurogastrointestinal encephalomyopathy: case reports.
Chronic intestinal pseudo-obstruction (CIPO) is a syndrome characterized by recurrent clinical episodes of intestinal obstruction… 
2004
2004
Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5…
Few studies have investigated the biological factors associated with sensitivity to bolus infusions of 5-fluorouracil (5FU… 
2003
2003
Cytoplasmic Uridine Phosphorylase of Rat Liver
Uridine phosphorylase (uridine:orthophosphate ribosyltransferase, EC 2.4.2.3) of rat liver cytoplasm has been purified 1900-fold… 
2001
2001
Heterogeneic distribution of thymidine phosphorylase between primary tumors and metastatic lesions of human pancreatic ductal carcinoma: implications for the efficacy of chemotherapy with 5-FU or its…
Abstract. Purpose: It has been suggested that the expression of thymidine phosphorylase (TdRPase) correlates with the malignant… 
Highly Cited
2000
Highly Cited
2000
Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy.
Thymidine phosphorylase (TP), an enzyme involved in the thymidine synthesis and degradation, has been shown to promote tumor… 
1998
1998
Effects of platelet-derived endothelial cell growth factor/thymidine phosphorylase, substrate, and products in a three-dimensional model of angiogenesis.
Platelet-derived endothelial cell growth factor/thymidine phosphorylase (PD-ECGF/TP) is associated with angiogenesis and the… 
1997
1997
376 直腸癌先進部近傍間質細胞における thym idine phosphorylase (TdRPase) 発現の意義について( 第50回日本消化器外科学会総会)
1975
1975
In vitro sensitivity of hemophilus influenzae and streptococcus pyogenes to co-trimoxazole.
  • W. Leers
  • Canadian Medical Association journal
  • 1975
  • Corpus ID: 45658674
The invitro testing of Hemophilus influenzae and Streptococcus pyogenes for co-trimoxazole sensitivity requires certain "defined… 
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